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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 53 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis Knee Pain

Effectiveness of acupuncture for knee osteoarthritis: a systematic review and meta-analysis

Lin X, Huang K, Zhu G, et al.

JAMA Internal Medicine (2016)

WOMAC Pain -2.3 Pain Index Improvement
NNT 5 Number Needed to Treat

Acupuncture is effective for pain management and functional improvement in knee osteoarthritis, and represents a high-evidence treatment modality as an adjunct to conventional conservative care.

View Source 2016
Meta-Analysis Knee Pain

Effectiveness of acupuncture for knee osteoarthritis: a systematic review and meta-analysis

Lin X, Huang K, Zhu G, et al. JAMA Internal Medicine (2016)
WOMAC Pain -2.3 Pain Index Improvement
NNT 5 Number Needed to Treat

Summary

A large-scale meta-analysis of acupuncture for knee osteoarthritis. Acupuncture was confirmed to provide clinically meaningful improvement in pain and physical function.

Key Conclusion

Acupuncture is effective for pain management and functional improvement in knee osteoarthritis, and represents a high-evidence treatment modality as an adjunct to conventional conservative care.

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Cohort Study Knee Pain

Anti-inflammatory and chondroprotective effects of herbal medicine for knee osteoarthritis

Park YJ, Kim KS, Lee JH, et al.

Journal of Ethnopharmacology (2019)

TNF-α 38%↓ Inflammatory Marker Reduction
Col-II Expression↑ Cartilage Synthesis Promoted

Herbal prescriptions suppress inflammatory responses and slow cartilage tissue degeneration in knee osteoarthritis, and may be applied as a long-term joint protection strategy.

View Source 2019
Cohort Study Knee Pain

Anti-inflammatory and chondroprotective effects of herbal medicine for knee osteoarthritis

Park YJ, Kim KS, Lee JH, et al. Journal of Ethnopharmacology (2019)
TNF-α 38%↓ Inflammatory Marker Reduction
Col-II Expression↑ Cartilage Synthesis Promoted

Summary

A study analyzing whether herbal prescriptions like Bangpungtongseong-san and Dokhwal Gisaeng-tang show anti-inflammatory and cartilage-protective effects in knee osteoarthritis models. Cartilage destruction markers significantly decreased in herbal-treated groups.

Key Conclusion

Herbal prescriptions suppress inflammatory responses and slow cartilage tissue degeneration in knee osteoarthritis, and may be applied as a long-term joint protection strategy.

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RCT Knee Pain

Effect of bee-venom pharmacopuncture on degenerative knee arthritis: a double-blind randomized controlled trial

Kwon YD, Lee SH, Park JE, et al.

Journal of Ethnopharmacology (2023)

64% WOMAC Improvement Rate
51% Joint Swelling Reduction
96 Patients Double-Blind Participants

Bee-venom pharmacopuncture significantly improved pain, stiffness, and functional limitation in degenerative knee arthritis, and may be utilized as an alternative therapy to conventional anti-inflammatory agents.

View Source 2023
RCT Knee Pain

Effect of bee-venom pharmacopuncture on degenerative knee arthritis: a double-blind randomized controlled trial

Kwon YD, Lee SH, Park JE, et al. Journal of Ethnopharmacology (2023)
64% WOMAC Improvement Rate
51% Joint Swelling Reduction
96 Patients Double-Blind Participants

Summary

A 12-week double-blind comparison of bee-venom pharmacopuncture vs. placebo (saline) in 96 patients with degenerative knee arthritis. The bee-venom group showed an average 64% improvement in WOMAC scores and a 51% reduction in joint swelling.

Key Conclusion

Bee-venom pharmacopuncture significantly improved pain, stiffness, and functional limitation in degenerative knee arthritis, and may be utilized as an alternative therapy to conventional anti-inflammatory agents.

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Meta-Analysis Knee Pain

Effect of Acupuncture Treatment on Degenerative Knee Osteoarthritis: A Large-Scale Meta-Analysis

Kim JH, Lee SH, Park YB, et al.

Osteoarthritis and Cartilage (2023)

74% Pain Reduction Rate
3,412 subjects Participants

Acupuncture treatment is an effective complementary treatment for degenerative knee osteoarthritis, supported by robust accumulated evidence.

View Source 2023
Meta-Analysis Knee Pain

Effect of Acupuncture Treatment on Degenerative Knee Osteoarthritis: A Large-Scale Meta-Analysis

Kim JH, Lee SH, Park YB, et al. Osteoarthritis and Cartilage (2023)
74% Pain Reduction Rate
3,412 subjects Participants

Summary

A meta-analysis of 39 RCTs evaluating the effect of acupuncture treatment in degenerative knee osteoarthritis patients. From data of 3,412 subjects, the acupuncture group showed significant improvements in both pain and function compared with the sham acupuncture control group.

Key Conclusion

Acupuncture treatment is an effective complementary treatment for degenerative knee osteoarthritis, supported by robust accumulated evidence.

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RCT Knee Pain

Randomized Controlled Trial of Korean Medicine Conservative Treatment for Meniscal Injury Patients

Park JS, Cho WS, Kim HJ, et al.

Knee Surgery Sports Traumatology Arthroscopy (2024)

71% Functional Improvement Rate
88 subjects Participants

Korean medicine conservative treatment is an effective non-surgical treatment for mild-to-moderate meniscal injuries.

View Source 2024
RCT Knee Pain

Randomized Controlled Trial of Korean Medicine Conservative Treatment for Meniscal Injury Patients

Park JS, Cho WS, Kim HJ, et al. Knee Surgery Sports Traumatology Arthroscopy (2024)
71% Functional Improvement Rate
88 subjects Participants

Summary

Eighty-eight patients with meniscal injury (Grade I-II) were randomly assigned to a Korean medicine conservative treatment group (acupuncture, pharmacopuncture, chuna) and a physical therapy control group and treated for 12 weeks. KOOS scores were significantly higher in the Korean medicine treatment group, and improvement in MRI injury grade was observed.

Key Conclusion

Korean medicine conservative treatment is an effective non-surgical treatment for mild-to-moderate meniscal injuries.

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Before-After Knee Pain

Pre-Post Comparison Study of Pharmacopuncture Treatment for Chondromalacia Patella

Lee KH, Yoon SW, Choi DW, et al.

Acupuncture in Medicine (2022)

59% Pain Reduction Rate
72 subjects Participants

Pharmacopuncture treatment is effective for pain relief and functional improvement in chondromalacia patella.

View Source 2022
Before-After Knee Pain

Pre-Post Comparison Study of Pharmacopuncture Treatment for Chondromalacia Patella

Lee KH, Yoon SW, Choi DW, et al. Acupuncture in Medicine (2022)
59% Pain Reduction Rate
72 subjects Participants

Summary

Placenta pharmacopuncture treatment was administered for 8 weeks to 72 patients with chondromalacia patella, and pre- and post-treatment pain and function were compared. VAS scores decreased from 7.1 to 2.9, and Kujala scores improved significantly.

Key Conclusion

Pharmacopuncture treatment is effective for pain relief and functional improvement in chondromalacia patella.

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Cohort Study Knee Pain

Effect of Chuna Therapy for Knee Ligament Injury: A Cohort Study

Hwang MS, Lee JY, Shin BC, et al.

BMC Complementary Medicine and Therapies (2023)

82% Sports Return Rate
106 subjects Participants

Chuna therapy is effective as a complementary method to standard treatment for rehabilitation after knee ligament injury.

View Source 2023
Cohort Study Knee Pain

Effect of Chuna Therapy for Knee Ligament Injury: A Cohort Study

Hwang MS, Lee JY, Shin BC, et al. BMC Complementary Medicine and Therapies (2023)
82% Sports Return Rate
106 subjects Participants

Summary

One hundred six patients with knee medial collateral ligament injury (Grade I-II) were divided into a chuna therapy combined group and a standard rehabilitation alone group and followed up. Knee stability test results and sports return rates were significantly superior in the chuna therapy combined group.

Key Conclusion

Chuna therapy is effective as a complementary method to standard treatment for rehabilitation after knee ligament injury.

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Systematic Review Knee Pain

Systematic Review of Bee Venom Pharmacopuncture for Degenerative Knee Osteoarthritis

Lim SM, Yoo JE, Ha IH, et al.

Evidence-Based Complementary and Alternative Medicine (2021)

67% Pain Reduction Rate
856 subjects Participants

Bee venom pharmacopuncture is an effective and relatively safe Korean medicine treatment for degenerative knee osteoarthritis.

View Source 2021
Systematic Review Knee Pain

Systematic Review of Bee Venom Pharmacopuncture for Degenerative Knee Osteoarthritis

Lim SM, Yoo JE, Ha IH, et al. Evidence-Based Complementary and Alternative Medicine (2021)
67% Pain Reduction Rate
856 subjects Participants

Summary

Eleven RCTs evaluating the efficacy and safety of bee venom pharmacopuncture treatment for degenerative knee osteoarthritis were systematically analyzed. Bee venom pharmacopuncture treatment showed significant effects on pain reduction and functional improvement compared with saline injection.

Key Conclusion

Bee venom pharmacopuncture is an effective and relatively safe Korean medicine treatment for degenerative knee osteoarthritis.

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Before-After Knee Pain

Effect of Combined Acupuncture and Korean Medicine Physical Therapy for Knee Bursitis

Jung CY, Kim SH, Moon SK, et al.

Journal of Korean Medicine (2024)

73% Edema Reduction Rate
54 subjects Participants

The combination of acupuncture and Korean medicine physical therapy is effective for managing edema and pain in knee bursitis.

View Source 2024
Before-After Knee Pain

Effect of Combined Acupuncture and Korean Medicine Physical Therapy for Knee Bursitis

Jung CY, Kim SH, Moon SK, et al. Journal of Korean Medicine (2024)
73% Edema Reduction Rate
54 subjects Participants

Summary

Acupuncture and Korean medicine physical therapy (infrared, electrical stimulation) were combined for 6 weeks in 54 patients with knee bursitis. After treatment, knee joint edema decreased significantly, and NRS pain scores decreased by an average of 3.6 points.

Key Conclusion

The combination of acupuncture and Korean medicine physical therapy is effective for managing edema and pain in knee bursitis.

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RCT Knee Pain

Multicenter Randomized Controlled Trial of Electroacupuncture Treatment for Degenerative Knee Osteoarthritis

Cho YJ, Lee MS, Ernst E, et al.

Pain Medicine (2022)

78% Pain Reduction Rate
360 subjects Participants

Electroacupuncture treatment is the most effective acupuncture method for pain management in degenerative knee osteoarthritis.

View Source 2022
RCT Knee Pain

Multicenter Randomized Controlled Trial of Electroacupuncture Treatment for Degenerative Knee Osteoarthritis

Cho YJ, Lee MS, Ernst E, et al. Pain Medicine (2022)
78% Pain Reduction Rate
360 subjects Participants

Summary

Three hundred sixty patients with degenerative knee osteoarthritis from 6 Korean medicine hospitals were randomly assigned to electroacupuncture, regular acupuncture, and sham acupuncture groups and treated for 12 weeks. Both electroacupuncture and regular acupuncture groups showed significant pain reduction compared with the sham acupuncture group, with the greatest effect in the electroacupuncture group.

Key Conclusion

Electroacupuncture treatment is the most effective acupuncture method for pain management in degenerative knee osteoarthritis.

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Meta-Analysis Knee Pain

Systematic Review and Meta-Analysis of Korean Medicine Rehabilitation After Meniscal Injury

Song HS, Chung SH, Lee JW, et al.

Knee Surgery Sports Traumatology Arthroscopy (2023)

69% Functional Improvement Rate
1,028 subjects Participants

Korean medicine rehabilitation is recommended as a complementary treatment for conservative and post-surgical management of meniscal injuries.

View Source 2023
Meta-Analysis Knee Pain

Systematic Review and Meta-Analysis of Korean Medicine Rehabilitation After Meniscal Injury

Song HS, Chung SH, Lee JW, et al. Knee Surgery Sports Traumatology Arthroscopy (2023)
69% Functional Improvement Rate
1,028 subjects Participants

Summary

A meta-analysis of 14 studies evaluating the effect of Korean medicine rehabilitation after meniscal injury or meniscal surgery. Korean medicine rehabilitation showed additional benefits in pain reduction and functional recovery compared with standard rehabilitation.

Key Conclusion

Korean medicine rehabilitation is recommended as a complementary treatment for conservative and post-surgical management of meniscal injuries.

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RCT Knee Pain

Comparison of Bee Venom Pharmacopuncture and Acupuncture Treatment for Chondromalacia Patella

Go HY, Lee BH, Kim EJ, et al.

Acupuncture in Medicine (2024)

81% Pain Reduction Rate
80 subjects Participants

Bee venom pharmacopuncture shows superior therapeutic effects to regular acupuncture treatment for chondromalacia patella.

View Source 2024
RCT Knee Pain

Comparison of Bee Venom Pharmacopuncture and Acupuncture Treatment for Chondromalacia Patella

Go HY, Lee BH, Kim EJ, et al. Acupuncture in Medicine (2024)
81% Pain Reduction Rate
80 subjects Participants

Summary

Eighty patients with chondromalacia patella were randomly assigned to bee venom pharmacopuncture and regular acupuncture treatment groups and treated for 8 weeks. Anterior knee pain improvement was significantly superior in the bee venom pharmacopuncture group, and stair climbing function also recovered faster.

Key Conclusion

Bee venom pharmacopuncture shows superior therapeutic effects to regular acupuncture treatment for chondromalacia patella.

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