Possible side effects vary by ingredient: ① Mahwang-containing formulas: temporary palpitation, insomnia, mouth dryness (mild, manageable), ② laxative herbs: loose stools (intentional, controlled), ③ rare cases: anxiety, increased heart rate. Minimized through: ① constitution-based prescription (avoid Mahwang for hypertension/heart disease), ② starting at low dose, ③ regular monitoring, ④ dose adjustment based on response. Contraindicated in pregnancy, severe hypertension, untreated heart disease.