금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 44 papers

Systematic Review Geum! Maek! Capsule Diet

Systematic Review of Weight Loss Effect and Safety of Mahuang-Containing Herbal Medicine

Cho SH, Yoon JH, Kim WK, et al.

BMC Complementary Medicine and Therapies (2024)

24 studies Number of Reviewed Studies
4.5kg Additional Weight Loss Effect

Mahuang herbal medicine at appropriate doses is effective for obesity treatment and can be used within established safety ranges.

Systematic Review Geum! Maek! Capsule Diet

Systematic Review of Weight Loss Effect and Safety of Mahuang-Containing Herbal Medicine

Cho SH, Yoon JH, Kim WK, et al. BMC Complementary Medicine and Therapies (2024)
24 studies Number of Reviewed Studies
4.5kg Additional Weight Loss Effect

Summary

The obesity treatment effect and safety of Mahuang (Ephedra sinica)-containing herbal medicine were systematically analyzed across 24 clinical studies. The Mahuang herbal medicine group showed an average additional weight reduction of 4.5 kg, and no cardiovascular adverse events occurred.

Key Conclusion

Mahuang herbal medicine at appropriate doses is effective for obesity treatment and can be used within established safety ranges.

RCT Geum! Maek! Capsule Diet

Appetite Suppression Effect of Auricular Acupuncture: A Randomized Double-Blind Study

Lee MH, Shin JC, Hwang DS, et al.

Complementary Therapies in Medicine (2022)

45% Appetite Reduction Rate
80 subjects Number of Participants

Auricular acupuncture has significant effects on appetite suppression and can be utilized as an adjunctive therapy for obesity treatment.

RCT Geum! Maek! Capsule Diet

Appetite Suppression Effect of Auricular Acupuncture: A Randomized Double-Blind Study

Lee MH, Shin JC, Hwang DS, et al. Complementary Therapies in Medicine (2022)
45% Appetite Reduction Rate
80 subjects Number of Participants

Summary

Eighty overweight adults were divided into an auricular acupuncture treatment group and a placebo group, and appetite changes were evaluated over 8 weeks. The auricular acupuncture group showed a 45% reduction in appetite scores (VAS), and snacking frequency decreased significantly.

Key Conclusion

Auricular acupuncture has significant effects on appetite suppression and can be utilized as an adjunctive therapy for obesity treatment.

Cohort Study Geum! Maek! Capsule Diet

Visceral Fat Reduction Effect of Combined Herbal Medicine Prescription: An Abdominal CT-Based Cohort Study

Park JH, Song MY, Cho JH, et al.

Journal of Ethnopharmacology (2023)

21.3cm² Visceral Fat Reduction
65 subjects Number of Participants

Combined herbal medicine prescriptions significantly reduce visceral fat and may contribute to metabolic syndrome prevention.

Cohort Study Geum! Maek! Capsule Diet

Visceral Fat Reduction Effect of Combined Herbal Medicine Prescription: An Abdominal CT-Based Cohort Study

Park JH, Song MY, Cho JH, et al. Journal of Ethnopharmacology (2023)
21.3cm² Visceral Fat Reduction
65 subjects Number of Participants

Summary

A combined herbal medicine prescription was administered for 12 weeks to 65 patients with visceral obesity (visceral fat area ≥100 cm² on abdominal CT), and visceral fat changes were measured by abdominal CT. Visceral fat area decreased by an average of 21.3 cm².

Key Conclusion

Combined herbal medicine prescriptions significantly reduce visceral fat and may contribute to metabolic syndrome prevention.

Meta-Analysis Geum! Maek! Capsule Diet

Meta-Analysis of Obesity Treatment Effect of Bangpungtongseong-san

Jung JY, Kim AR, Choi JB, et al.

Phytomedicine (2021)

MD -3.21kg Mean Difference
16 studies Number of Reviewed RCTs

Bangpungtongseong-san demonstrates significant effects on weight and body fat reduction in obese patients with a high level of evidence.

Meta-Analysis Geum! Maek! Capsule Diet

Meta-Analysis of Obesity Treatment Effect of Bangpungtongseong-san

Jung JY, Kim AR, Choi JB, et al. Phytomedicine (2021)
MD -3.21kg Mean Difference
16 studies Number of Reviewed RCTs

Summary

The obesity treatment effect of Bangpungtongseong-san was meta-analyzed across 16 randomized controlled trials. The Bangpungtongseong-san group showed significant weight reduction (MD: -3.21 kg, 95% CI: -4.15 to -2.27) and body fat percentage reduction.

Key Conclusion

Bangpungtongseong-san demonstrates significant effects on weight and body fat reduction in obese patients with a high level of evidence.

Before-After Geum! Maek! Capsule Diet

Study on Basal Metabolic Rate Enhancement Effect of Korean Medicine Diet Capsules

Seo AR, Lim ST, Yoo HJ, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

8.7% Basal Metabolic Rate Increase
50 subjects Number of Participants

Korean medicine diet capsules increase basal metabolic rate to promote weight loss.

Before-After Geum! Maek! Capsule Diet

Study on Basal Metabolic Rate Enhancement Effect of Korean Medicine Diet Capsules

Seo AR, Lim ST, Yoo HJ, et al. Evidence-Based Complementary and Alternative Medicine (2024)
8.7% Basal Metabolic Rate Increase
50 subjects Number of Participants

Summary

Herbal medicine extract capsules were administered for 8 weeks to 50 obese women, and changes in basal metabolic rate (BMR) were measured by indirect calorimetry. The capsule administration group showed an average BMR increase of 8.7%, accompanied by weight reduction.

Key Conclusion

Korean medicine diet capsules increase basal metabolic rate to promote weight loss.

Before-After Geum! Maek! Capsule Diet

Effect of Acupuncture on Leptin and Ghrelin Hormones in Obese Patients

Won JH, Byun SH, Kim DY, et al.

BMC Complementary Medicine and Therapies (2023)

22% Ghrelin Reduction Rate
60 subjects Number of Participants

Acupuncture normalizes appetite-regulating hormones and provides a physiological basis for obesity treatment.

Before-After Geum! Maek! Capsule Diet

Effect of Acupuncture on Leptin and Ghrelin Hormones in Obese Patients

Won JH, Byun SH, Kim DY, et al. BMC Complementary Medicine and Therapies (2023)
22% Ghrelin Reduction Rate
60 subjects Number of Participants

Summary

Blood leptin and ghrelin concentrations before and after acupuncture treatment were measured in 60 obese patients. After 8 weeks of acupuncture, leptin decreased by 18% and ghrelin decreased by 22%, demonstrating normalization of appetite-regulating hormones.

Key Conclusion

Acupuncture normalizes appetite-regulating hormones and provides a physiological basis for obesity treatment.

RCT Geum! Maek! Capsule Diet

Effect of Sasang Constitutional Tailored Treatment for Taeumin Obesity: A Randomized Controlled Trial

Baek YH, Jang ES, Lee SW, et al.

Journal of Korean Medicine (2022)

8.2kg Tailored Group Weight Reduction
70 subjects Number of Participants

Sasang constitutional medicine-based tailored Korean medicine obesity treatment demonstrates superior weight loss effects compared to general prescriptions.

RCT Geum! Maek! Capsule Diet

Effect of Sasang Constitutional Tailored Treatment for Taeumin Obesity: A Randomized Controlled Trial

Baek YH, Jang ES, Lee SW, et al. Journal of Korean Medicine (2022)
8.2kg Tailored Group Weight Reduction
70 subjects Number of Participants

Summary

Seventy Taeumin obese patients were divided into a constitutional tailored herbal medicine group and a general herbal medicine group, and treatment effects were compared over 16 weeks. The constitutional tailored group showed significantly greater weight reduction (8.2 kg vs 5.1 kg) and waist circumference reduction.

Key Conclusion

Sasang constitutional medicine-based tailored Korean medicine obesity treatment demonstrates superior weight loss effects compared to general prescriptions.

Cohort Study Geum! Maek! Capsule Diet

Correlation Between Gut Microbiome Changes and Weight Loss in Korean Medicine Diet

Moon JY, Cha WS, Ko SG, et al.

Journal of Ethnopharmacology (2024)

45 subjects Number of Participants
r=0.72 Correlation Coefficient

Korean medicine diet improves gut microbiome balance, which acts as one of the mechanisms for weight reduction.

Cohort Study Geum! Maek! Capsule Diet

Correlation Between Gut Microbiome Changes and Weight Loss in Korean Medicine Diet

Moon JY, Cha WS, Ko SG, et al. Journal of Ethnopharmacology (2024)
45 subjects Number of Participants
r=0.72 Correlation Coefficient

Summary

Gut microbiome (16S rRNA) changes were analyzed in 45 patients receiving Korean medicine diet treatment. After treatment, the Firmicutes/Bacteroidetes ratio normalized, and these changes showed a significant correlation with weight reduction.

Key Conclusion

Korean medicine diet improves gut microbiome balance, which acts as one of the mechanisms for weight reduction.

Meta-Analysis Geum! Maek! Capsule Diet

Abdominal Obesity Treatment Effect of Combined Electroacupuncture and Herbal Medicine: A Systematic Review and Meta-Analysis

Ahn CB, Kim CH, Song HS, et al.

Complementary Therapies in Medicine (2023)

MD -4.82cm Waist Circumference Reduction
11 studies Number of Reviewed RCTs

Combined electroacupuncture and herbal medicine demonstrates superior effects for abdominal obesity treatment compared to monotherapy.

Meta-Analysis Geum! Maek! Capsule Diet

Abdominal Obesity Treatment Effect of Combined Electroacupuncture and Herbal Medicine: A Systematic Review and Meta-Analysis

Ahn CB, Kim CH, Song HS, et al. Complementary Therapies in Medicine (2023)
MD -4.82cm Waist Circumference Reduction
11 studies Number of Reviewed RCTs

Summary

The abdominal obesity improvement effect of combined electroacupuncture and herbal medicine treatment was meta-analyzed across 11 RCTs. The combined treatment group showed significantly greater waist circumference reduction (MD: -4.82 cm) than the monotherapy group.

Key Conclusion

Combined electroacupuncture and herbal medicine demonstrates superior effects for abdominal obesity treatment compared to monotherapy.

Before-After Geum! Maek! Capsule Diet

Insulin Resistance Improvement Effect of Korean Medicine Obesity Treatment

Shin AS, Lee JE, Kim NI, et al.

Phytomedicine (2022)

33% HOMA-IR Improvement Rate
55 subjects Number of Participants

Korean medicine obesity treatment improves insulin resistance along with weight loss and contributes to metabolic health.

Before-After Geum! Maek! Capsule Diet

Insulin Resistance Improvement Effect of Korean Medicine Obesity Treatment

Shin AS, Lee JE, Kim NI, et al. Phytomedicine (2022)
33% HOMA-IR Improvement Rate
55 subjects Number of Participants

Summary

Herbal medicine prescriptions were administered for 12 weeks to 55 patients with obesity and insulin resistance, and HOMA-IR changes were measured. HOMA-IR decreased from an average of 2.1 to 1.4, with significant improvement in insulin sensitivity.

Key Conclusion

Korean medicine obesity treatment improves insulin resistance along with weight loss and contributes to metabolic health.

RCT Geum! Maek! Capsule Diet

DEXA Analysis of Body Fat Distribution Changes After Herbal Medicine Capsule Administration

Go HY, Park YC, Lee NR, et al.

Evidence-Based Complementary and Alternative Medicine (2021)

3.8kg Body Fat Reduction
40 subjects Number of Participants

Herbal medicine capsules have effects of selectively reducing abdominal fat along with overall body fat reduction.

RCT Geum! Maek! Capsule Diet

DEXA Analysis of Body Fat Distribution Changes After Herbal Medicine Capsule Administration

Go HY, Park YC, Lee NR, et al. Evidence-Based Complementary and Alternative Medicine (2021)
3.8kg Body Fat Reduction
40 subjects Number of Participants

Summary

Herbal medicine capsules were administered for 10 weeks to 40 overweight adults, and body fat distribution changes were analyzed using DEXA. Total body fat decreased by 3.8 kg, with selectively greater reduction particularly in abdominal fat.

Key Conclusion

Herbal medicine capsules have effects of selectively reducing abdominal fat along with overall body fat reduction.

Cohort Study Geum! Maek! Capsule Diet

Retrospective Analysis of Korean Medicine Treatment Compliance and Long-Term Weight Maintenance in Obese Patients

Yim MH, Kim JE, Choi SM, et al.

Journal of Korean Medicine (2023)

78% Weight Maintenance Rate
180 subjects Number of Participants

High compliance with Korean medicine obesity treatment shows a strong correlation with long-term weight maintenance.

Cohort Study Geum! Maek! Capsule Diet

Retrospective Analysis of Korean Medicine Treatment Compliance and Long-Term Weight Maintenance in Obese Patients

Yim MH, Kim JE, Choi SM, et al. Journal of Korean Medicine (2023)
78% Weight Maintenance Rate
180 subjects Number of Participants

Summary

One hundred eighty patients who completed Korean medicine obesity treatment were retrospectively followed for 12 months, and weight maintenance rates were analyzed. The high compliance group maintained 78% of weight loss at 12 months after treatment.

Key Conclusion

High compliance with Korean medicine obesity treatment shows a strong correlation with long-term weight maintenance.