금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
🔍

Total 53 papers

Meta-Analysis Knee Pain

Network Meta-Analysis of Herbal Medicine Treatment for Degenerative Knee Osteoarthritis

Woo HS, Kim TH, Kang JW, et al.

Journal of Ethnopharmacology (2023)

1st-2nd rank Efficacy Ranking
45 studies Analyzed Studies

Banggihwanggi-tang and Dokhwalgisaeng-tang are the most effective herbal prescriptions for degenerative knee osteoarthritis.

Meta-Analysis Knee Pain

Network Meta-Analysis of Herbal Medicine Treatment for Degenerative Knee Osteoarthritis

Woo HS, Kim TH, Kang JW, et al. Journal of Ethnopharmacology (2023)
1st-2nd rank Efficacy Ranking
45 studies Analyzed Studies

Summary

A network meta-analysis of 45 RCTs was conducted to compare the effects of 17 herbal prescriptions used for degenerative knee osteoarthritis. Banggihwanggi-tang and Dokhwalgisaeng-tang showed the highest rankings in pain reduction.

Key Conclusion

Banggihwanggi-tang and Dokhwalgisaeng-tang are the most effective herbal prescriptions for degenerative knee osteoarthritis.

Case Study Knee Pain

Case Series of Acupuncture Treatment for Knee Ligament Injury

Bae GS, Yun KJ, Im JG, et al.

Journal of Korean Medicine (2021)

67% Ligament Recovery Rate
6 subjects Participants

The combination of acupuncture treatment and pharmacopuncture shows potential as conservative treatment for partial anterior cruciate ligament tears.

Case Study Knee Pain

Case Series of Acupuncture Treatment for Knee Ligament Injury

Bae GS, Yun KJ, Im JG, et al. Journal of Korean Medicine (2021)
67% Ligament Recovery Rate
6 subjects Participants

Summary

A case series in which acupuncture treatment and pharmacopuncture were administered for 12 weeks to 6 patients with partial anterior cruciate ligament tears. Lysholm scores improved in all patients, and recovery of ligament continuity on MRI was observed in 4 patients.

Key Conclusion

The combination of acupuncture treatment and pharmacopuncture shows potential as conservative treatment for partial anterior cruciate ligament tears.

RCT Knee Pain

Randomized Controlled Trial of Chuna Therapy for Degenerative Knee Osteoarthritis

Nam DH, Kang JW, Park TY, et al.

Osteoarthritis and Cartilage (2022)

72% Stiffness Improvement Rate
120 subjects Participants

Chuna therapy shows effects equivalent to or better than joint mobilization for improving joint stiffness in degenerative knee osteoarthritis.

RCT Knee Pain

Randomized Controlled Trial of Chuna Therapy for Degenerative Knee Osteoarthritis

Nam DH, Kang JW, Park TY, et al. Osteoarthritis and Cartilage (2022)
72% Stiffness Improvement Rate
120 subjects Participants

Summary

One hundred twenty patients with degenerative knee osteoarthritis (K-L Grade II-III) were randomly assigned to chuna therapy and joint mobilization groups and treated for 8 weeks. Both groups showed significant improvements, with superior improvement in joint stiffness in the chuna therapy group.

Key Conclusion

Chuna therapy shows effects equivalent to or better than joint mobilization for improving joint stiffness in degenerative knee osteoarthritis.

Narrative Review Knee Pain

Narrative Review of Korean Medicine Treatment for Knee Bursitis

Son CG, Ko SJ, Kwon OJ, et al.

BMC Complementary Medicine and Therapies (2020)

18 studies Analyzed Studies
Insufficient Current Evidence Level

Accumulation of clinical evidence for Korean medicine treatment of knee bursitis is needed.

Narrative Review Knee Pain

Narrative Review of Korean Medicine Treatment for Knee Bursitis

Son CG, Ko SJ, Kwon OJ, et al. BMC Complementary Medicine and Therapies (2020)
18 studies Analyzed Studies
Insufficient Current Evidence Level

Summary

The current status of Korean medicine treatment for knee bursitis was narratively reviewed. Acupuncture, cupping, and herbal medicine are being utilized, but high-quality clinical evidence is lacking, and future research directions were proposed.

Key Conclusion

Accumulation of clinical evidence for Korean medicine treatment of knee bursitis is needed.

Cross-Sectional Knee Pain

Cross-Sectional Analysis of Korean Medicine Physical Therapy for Degenerative Knee Osteoarthritis

Lee AR, Kim MR, Ha IH, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

87% Treatment Satisfaction
2,130 subjects Participants

Korean medicine physical therapy is widely utilized for degenerative knee osteoarthritis patients and shows high satisfaction.

Cross-Sectional Knee Pain

Cross-Sectional Analysis of Korean Medicine Physical Therapy for Degenerative Knee Osteoarthritis

Lee AR, Kim MR, Ha IH, et al. Evidence-Based Complementary and Alternative Medicine (2023)
87% Treatment Satisfaction
2,130 subjects Participants

Summary

Data from 2,130 patients who received Korean medicine physical therapy for degenerative knee osteoarthritis at Korean medicine institutions nationwide were analyzed. Infrared therapy, cupping, and electroacupuncture were utilized in that order, and satisfaction with combined treatment was higher than with single treatment.

Key Conclusion

Korean medicine physical therapy is widely utilized for degenerative knee osteoarthritis patients and shows high satisfaction.

RCT Knee Pain

Randomized Controlled Trial of Combined Acupuncture and Exercise Therapy for Chondromalacia Patella

Choi JH, Shin MS, Song MY, et al.

Pain Medicine (2024)

76% Functional Improvement Rate
90 subjects Participants

The combination of acupuncture treatment and exercise therapy is an effective treatment strategy for chondromalacia patella.

RCT Knee Pain

Randomized Controlled Trial of Combined Acupuncture and Exercise Therapy for Chondromalacia Patella

Choi JH, Shin MS, Song MY, et al. Pain Medicine (2024)
76% Functional Improvement Rate
90 subjects Participants

Summary

Ninety patients with chondromalacia patella were assigned to acupuncture + exercise therapy and exercise therapy alone groups and treated for 10 weeks. Kujala scores and squat pain improved significantly more in the combination group.

Key Conclusion

The combination of acupuncture treatment and exercise therapy is an effective treatment strategy for chondromalacia patella.

Cohort Study Knee Pain

Anti-Inflammatory Effect of Pharmacopuncture Treatment for Degenerative Knee Osteoarthritis: A Cohort Study

Kim AR, Jung SY, Noh SM, et al.

Journal of Ethnopharmacology (2022)

52% IL-1β Reduction Rate
145 subjects Participants

Hwangnyeonhaedok-tang pharmacopuncture effectively reduces intra-articular inflammation in degenerative knee osteoarthritis.

Cohort Study Knee Pain

Anti-Inflammatory Effect of Pharmacopuncture Treatment for Degenerative Knee Osteoarthritis: A Cohort Study

Kim AR, Jung SY, Noh SM, et al. Journal of Ethnopharmacology (2022)
52% IL-1β Reduction Rate
145 subjects Participants

Summary

Hwangnyeonhaedok-tang pharmacopuncture was administered for 12 weeks to 145 patients with degenerative knee osteoarthritis, and inflammatory markers in joint fluid were analyzed. IL-1β and TNF-α levels decreased significantly and correlated with clinical symptom improvement.

Key Conclusion

Hwangnyeonhaedok-tang pharmacopuncture effectively reduces intra-articular inflammation in degenerative knee osteoarthritis.

RCT Knee Pain

Effect of Korean Medicine Rehabilitation Program After Knee Ligament Injury

Shin HK, Park EH, Kim GH, et al.

Knee Surgery Sports Traumatology Arthroscopy (2023)

85% Functional Recovery Rate
74 subjects Participants

Korean medicine rehabilitation promotes recovery after anterior cruciate ligament reconstruction.

RCT Knee Pain

Effect of Korean Medicine Rehabilitation Program After Knee Ligament Injury

Shin HK, Park EH, Kim GH, et al. Knee Surgery Sports Traumatology Arthroscopy (2023)
85% Functional Recovery Rate
74 subjects Participants

Summary

Seventy-four patients after anterior cruciate ligament reconstruction were divided into a Korean medicine rehabilitation combined group and a standard rehabilitation alone group and followed up for 24 weeks. Knee flexion range of motion recovery was faster in the combination group, and muscle strength recovery was also superior.

Key Conclusion

Korean medicine rehabilitation promotes recovery after anterior cruciate ligament reconstruction.

RCT Knee Pain

Dose-Response Study of Bee Venom Pharmacopuncture for Degenerative Knee Osteoarthritis

Kwon CY, Kang JW, Lee BH, et al.

Acupuncture in Medicine (2021)

High-dose > low-dose Dose Response
135 subjects Participants

Bee venom pharmacopuncture shows dose-dependent effects, and optimal dose balancing safety and efficacy is needed.

RCT Knee Pain

Dose-Response Study of Bee Venom Pharmacopuncture for Degenerative Knee Osteoarthritis

Kwon CY, Kang JW, Lee BH, et al. Acupuncture in Medicine (2021)
High-dose > low-dose Dose Response
135 subjects Participants

Summary

One hundred thirty-five patients with degenerative knee osteoarthritis were assigned to low-dose bee venom pharmacopuncture, high-dose, and control groups and treated for 8 weeks. The pain reduction effect was greatest in the high-dose group, but local reaction frequency was also higher, confirming the importance of optimal dose selection.

Key Conclusion

Bee venom pharmacopuncture shows dose-dependent effects, and optimal dose balancing safety and efficacy is needed.

Before-After Knee Pain

Pre-Post Comparison Study of Herbal Medicine Treatment for Meniscal Injury

Moon SK, Jung WS, Cho KH, et al.

BMC Complementary Medicine and Therapies (2024)

38% MRI Improvement Rate
62 subjects Participants

Herbal medicine treatment can contribute to symptom improvement and tissue recovery in meniscal injuries.

Before-After Knee Pain

Pre-Post Comparison Study of Herbal Medicine Treatment for Meniscal Injury

Moon SK, Jung WS, Cho KH, et al. BMC Complementary Medicine and Therapies (2024)
38% MRI Improvement Rate
62 subjects Participants

Summary

Modified Danggwisusan was administered for 12 weeks to 62 patients with meniscal injury, and pre- and post-treatment pain, function, and MRI findings were compared. The KOOS pain subscale improved significantly, and improvement in MRI signal changes was observed in 38% of patients.

Key Conclusion

Herbal medicine treatment can contribute to symptom improvement and tissue recovery in meniscal injuries.

Cohort Study Knee Pain

Long-Term Effect of Acupuncture Treatment for Degenerative Knee Osteoarthritis: A 1-Year Follow-Up Study

Ha IH, Lee JH, Shin JS, et al.

Osteoarthritis and Cartilage (2024)

6 months Effect Duration
200 subjects Participants

The effects of acupuncture treatment are sustained long-term after treatment termination, making it suitable for long-term management of degenerative knee osteoarthritis.

Cohort Study Knee Pain

Long-Term Effect of Acupuncture Treatment for Degenerative Knee Osteoarthritis: A 1-Year Follow-Up Study

Ha IH, Lee JH, Shin JS, et al. Osteoarthritis and Cartilage (2024)
6 months Effect Duration
200 subjects Participants

Summary

Two hundred patients with degenerative knee osteoarthritis received acupuncture treatment for 12 weeks and were followed for 1 year. Pain reduction effects were maintained for 6 months after treatment termination, and significant improvement from baseline was sustained at the 1-year point.

Key Conclusion

The effects of acupuncture treatment are sustained long-term after treatment termination, making it suitable for long-term management of degenerative knee osteoarthritis.

Before-After Knee Pain

Effect of Cupping Treatment for Knee Bursitis: A Pre-Post Comparison Study

Oh MS, Ahn YJ, Min BW, et al.

Journal of Korean Medicine (2022)

42% Edema Reduction Rate
42 subjects Participants

Cupping treatment is an effective complementary treatment for managing edema and pain in knee bursitis.

Before-After Knee Pain

Effect of Cupping Treatment for Knee Bursitis: A Pre-Post Comparison Study

Oh MS, Ahn YJ, Min BW, et al. Journal of Korean Medicine (2022)
42% Edema Reduction Rate
42 subjects Participants

Summary

Wet cupping treatment was administered for 4 weeks to 42 patients with knee bursitis. After treatment, joint edema decreased by an average of 42%, and pain and walking ability significantly improved.

Key Conclusion

Cupping treatment is an effective complementary treatment for managing edema and pain in knee bursitis.