금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

📅 Book Appointment 📋 Geummaek Herbal Medicine 💬 Reviews 📝 Health Columns
Research Papers
🔍

Total 84 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cross-Sectional Men's Health / Urology

Antibacterial and Anti-Inflammatory Effect of Yongdamsagan-tang on Male Genital Infections: A Cross-Sectional Study

차현석, 김진우, 문승재, et al.

Journal of Microbiology and Biotechnology (2023)

3.8 days Treatment Period Shortened
48 subjects Number of Subjects
p=0.008 Statistical Significance

Yongdamsagan-tang enhances anti-inflammatory effects as an antibiotic adjunct treatment for male genital infections and shortens treatment duration.

View Source 2023
Cross-Sectional Men's Health / Urology

Antibacterial and Anti-Inflammatory Effect of Yongdamsagan-tang on Male Genital Infections: A Cross-Sectional Study

차현석, 김진우, 문승재, et al. Journal of Microbiology and Biotechnology (2023)
3.8 days Treatment Period Shortened
48 subjects Number of Subjects
p=0.008 Statistical Significance

Summary

A cross-sectional study analyzing the antibacterial and anti-inflammatory effect of Yongdamsagan-tang in 48 male patients with genital infections (epididymitis, seminal vesiculitis). With antibiotic combination, the Yongdamsagan-tang addition group showed faster decreases in CRP and semen leukocyte levels, and symptom resolution period was shortened by an average of 3.8 days.

Key Conclusion

Yongdamsagan-tang enhances anti-inflammatory effects as an antibiotic adjunct treatment for male genital infections and shortens treatment duration.

View Full Paper
Before-After Men's Health / Urology

Effect of Modified Dojeok-san on Residual Symptoms After Urethritis: A Pre-Post Comparison Study

안성호, 배진혁, 홍유진, et al.

대한한방내과학회지 (2024)

73.1% VAS Reduction Rate
36 subjects Number of Subjects
6 weeks Treatment Period

Modified Dojeok-san is effective for alleviating residual urethral symptoms after antibiotic treatment, with a mechanism through local inflammatory response suppression confirmed.

View Source 2024
Before-After Men's Health / Urology

Effect of Modified Dojeok-san on Residual Symptoms After Urethritis: A Pre-Post Comparison Study

안성호, 배진혁, 홍유진, et al. 대한한방내과학회지 (2024)
73.1% VAS Reduction Rate
36 subjects Number of Subjects
6 weeks Treatment Period

Summary

A pre-post comparison study analyzing the effect of modified Dojeok-san in 36 men with persistent urethral discomfort after antibiotic treatment. After 6 weeks of administration, urethral burning VAS decreased from an average of 6.7 to 1.8, and urinary frequency and residual urine sensation also improved significantly. Urinary cytokine (IL-8, IL-1β) levels also decreased.

Key Conclusion

Modified Dojeok-san is effective for alleviating residual urethral symptoms after antibiotic treatment, with a mechanism through local inflammatory response suppression confirmed.

View Full Paper
Case Study Men's Health / Urology

Effect of Taeumjowi-tang on Metabolic Indicator Improvement for Visceral Fat-Type Male Obesity: A Case Study

김하준, 이채원, 정태욱, et al.

Metabolism (2023)

31.4 cm² Visceral Fat Reduction
10 cases Number of Cases
12 weeks Treatment Period

Taeumjowi-tang is an effective and safe treatment for visceral fat reduction and metabolic indicator improvement in visceral fat-type male obesity.

View Source 2023
Case Study Men's Health / Urology

Effect of Taeumjowi-tang on Metabolic Indicator Improvement for Visceral Fat-Type Male Obesity: A Case Study

김하준, 이채원, 정태욱, et al. Metabolism (2023)
31.4 cm² Visceral Fat Reduction
10 cases Number of Cases
12 weeks Treatment Period

Summary

A case study on Taeumjowi-tang treatment in 10 male patients with visceral fat-type obesity (CT visceral fat area ≥100 cm²). After 12 weeks of administration, visceral fat area decreased by an average of 31.4 cm², and metabolic indicators including fasting blood glucose, HbA1c, triglycerides, and LDL-C also improved significantly. Liver function indicators (AST/ALT) remained within normal ranges.

Key Conclusion

Taeumjowi-tang is an effective and safe treatment for visceral fat reduction and metabolic indicator improvement in visceral fat-type male obesity.

View Full Paper
Cohort Study Men's Health / Urology

Immediate Analgesic Effect of Auricular Acupuncture Treatment for Ureteral Stone Colic: A Cohort Study

홍석현, 배승우, 김태윤, et al.

Acupuncture in Medicine (2023)

59.0% VAS Reduction Rate
72 subjects Number of Subjects
30 minutes Effect Onset Time

Auricular acupuncture treatment is an immediate and effective analgesic method for ureteral stone colic, with high value as adjunctive treatment in emergency situations.

View Source 2023
Cohort Study Men's Health / Urology

Immediate Analgesic Effect of Auricular Acupuncture Treatment for Ureteral Stone Colic: A Cohort Study

홍석현, 배승우, 김태윤, et al. Acupuncture in Medicine (2023)
59.0% VAS Reduction Rate
72 subjects Number of Subjects
30 minutes Effect Onset Time

Summary

A cohort study analyzing the analgesic effect of auricular acupuncture treatment in 72 men who visited the emergency room for ureteral stone colic. Thirty minutes after auricular acupuncture stimulation at Kidney, Sympathetic, and Shenmen acupoints, VAS pain scores decreased from an average of 7.8 to 3.2, and the need for additional analgesic administration was significantly lower.

Key Conclusion

Auricular acupuncture treatment is an immediate and effective analgesic method for ureteral stone colic, with high value as adjunctive treatment in emergency situations.

View Full Paper
Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al.

BMC Urology (2024)

68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

View Source 2024
Cross-Sectional Men's Health / Urology

Immune Regulatory Effect of Bojungikgi-tang on Recurrent Urinary Tract Infections in Men: A Cross-Sectional Study

권정민, 유승호, 장동수, et al. BMC Urology (2024)
68.9% Recurrence Rate Reduction
58 subjects Number of Subjects
12 months Follow-up Period

Summary

A cross-sectional study analyzing the immune regulatory effect of Bojungikgi-tang in 58 men with recurrent urinary tract infections (≥3/year). The Bojungikgi-tang administration group showed increased IgA secretion in urine, and expression of urinary mucosal defense factor Tamm-Horsfall protein also improved. Recurrence rates decreased significantly at 12-month follow-up.

Key Conclusion

Bojungikgi-tang is effective for preventing recurrent urinary tract infections in men, and a mechanism through urinary mucosal local immune enhancement was confirmed.

View Full Paper
Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al.

Complementary Therapies in Clinical Practice (2023)

2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

View Source 2023
Before-After Men's Health / Urology

Anti-Inflammatory and Voiding Function Improvement Effect of Oryeong-san on Male Cystitis: A Pre-Post Comparison Study

최동헌, 김세준, 이우택, et al. Complementary Therapies in Clinical Practice (2023)
2.1 days Symptom Resolution Shortened
44 subjects Number of Subjects
p=0.012 Statistical Significance

Summary

A pre-post comparison study analyzing the anti-inflammatory and voiding function improvement effect of Oryeong-san in 44 male patients with acute cystitis. With combined antibiotic administration, the Oryeong-san addition group showed faster urinary WBC reduction speed, and dysuria resolution period was shortened by an average of 2.1 days, with lower recurrence rates.

Key Conclusion

Oryeong-san is effective for promoting inflammation resolution and shortening symptom improvement period as adjunctive to antibiotic treatment for male cystitis.

View Full Paper
Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al.

대한한방피부미용학회지 (2024)

18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

View Source 2024
Case Study Men's Health / Urology

Hair Regrowth Effect of Pharmacopuncture Treatment for Androgenetic Alopecia (AGA): 12 Case Reports

양현수, 오지훈, 김래환, et al. 대한한방피부미용학회지 (2024)
18.7 strands/cm² Hair Density Increase
12 cases Number of Cases
16 weeks Treatment Period

Summary

A case report on 12 patients with androgenetic alopecia (AGA, Hamilton-Norwood classification III-IV) treated with Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture. After 16 weeks of scalp pharmacopuncture twice weekly, hair density increased by an average of 18.7 strands/cm², and hair thickness also increased significantly. Scalp blood flow improvement was confirmed by ultrasound examination.

Key Conclusion

Polygoni Multiflori Radix-Biota Orientalis pharmacopuncture is effective for improving hair density and thickness in androgenetic alopecia patients, with scalp microcirculation improvement as the main mechanism.

View Full Paper
Narrative Review Men's Health / Urology

Efficacy and Safety of Korean Medicine Treatment for Male Hair Loss: A Narrative Literature Review

나승현, 전호영, 백지원, et al.

Dermatologic Therapy (2023)

38 studies Analyzed Studies
2.3% Adverse Reaction Rate
15 years Analysis Period

Korean medicine treatment is an effective and safe treatment alternative for male hair loss and can be particularly recommended for patients concerned about drug side effects.

View Source 2023
Narrative Review Men's Health / Urology

Efficacy and Safety of Korean Medicine Treatment for Male Hair Loss: A Narrative Literature Review

나승현, 전호영, 백지원, et al. Dermatologic Therapy (2023)
38 studies Analyzed Studies
2.3% Adverse Reaction Rate
15 years Analysis Period

Summary

A narrative literature review comprehensively analyzing the efficacy and safety of Korean medicine treatment (herbal medicine, acupuncture, pharmacopuncture, scalp acupuncture) for male hair loss. Thirty-eight clinical studies over the past 15 years were analyzed, with combined herbal medicine and pharmacopuncture treatment showing the highest effects, and adverse reaction incidence rates significantly lower than finasteride.

Key Conclusion

Korean medicine treatment is an effective and safe treatment alternative for male hair loss and can be particularly recommended for patients concerned about drug side effects.

View Full Paper
Systematic Review Men's Health / Urology

Effect of Bangpungtongseong-san on Visceral Fat Reduction for Male Abdominal Obesity: A Systematic Review and Meta-Analysis

장서진, 김민규, 이하은, et al.

Obesity Reviews (2024)

4.7 cm Waist Circumference Reduction
23.4 cm² Visceral Fat Area Reduction
1,089 subjects Total Subjects

Bangpungtongseong-san significantly reduces visceral fat in male abdominal obesity patients and is also effective for improving metabolic syndrome risk factors.

View Source 2024
Systematic Review Men's Health / Urology

Effect of Bangpungtongseong-san on Visceral Fat Reduction for Male Abdominal Obesity: A Systematic Review and Meta-Analysis

장서진, 김민규, 이하은, et al. Obesity Reviews (2024)
4.7 cm Waist Circumference Reduction
23.4 cm² Visceral Fat Area Reduction
1,089 subjects Total Subjects

Summary

A systematic review and meta-analysis analyzing the effect of Bangpungtongseong-san on visceral fat reduction in men with abdominal obesity. Sixteen clinical trials (total 1,089 subjects) were included, and the Bangpungtongseong-san administration group showed an average waist circumference reduction of 4.7 cm and visceral fat area reduction of 23.4 cm².

Key Conclusion

Bangpungtongseong-san significantly reduces visceral fat in male abdominal obesity patients and is also effective for improving metabolic syndrome risk factors.

View Full Paper
Meta-Analysis Men's Health / Urology

Weight and Body Composition Changes with Combined Acupuncture-Electroacupuncture Treatment for Male Obesity: A Meta-Analysis

이진혁, 송민호, 황재우, et al.

Acupuncture in Medicine (2024)

3.8 kg Average Weight Reduction
2.9% Body Fat Percentage Reduction
756 subjects Total Subjects

Combined acupuncture-electroacupuncture treatment is effective for weight and body composition improvement in male obesity patients, and synergistic effects are expected when combined with lifestyle modification.

View Source 2024
Meta-Analysis Men's Health / Urology

Weight and Body Composition Changes with Combined Acupuncture-Electroacupuncture Treatment for Male Obesity: A Meta-Analysis

이진혁, 송민호, 황재우, et al. Acupuncture in Medicine (2024)
3.8 kg Average Weight Reduction
2.9% Body Fat Percentage Reduction
756 subjects Total Subjects

Summary

A meta-analysis analyzing weight and body composition changes with combined acupuncture-electroacupuncture treatment in men with BMI 25 or higher. Twelve randomized controlled trials (total 756 subjects) were included, confirming an average weight reduction of 3.8 kg and body fat percentage reduction of 2.9% in the treatment group. Electroacupuncture centered on abdominal acupoints was most effective.

Key Conclusion

Combined acupuncture-electroacupuncture treatment is effective for weight and body composition improvement in male obesity patients, and synergistic effects are expected when combined with lifestyle modification.

View Full Paper
RCT Men's Health / Urology

Antidepressant Effect of Guibi-tang on Male Climacteric Depression: A Randomized Controlled Trial

곽재현, 문지영, 차승환, et al.

Journal of Affective Disorders (2023)

49.3% BDI Score Reduction Rate
82 subjects Number of Subjects
p<0.001 Statistical Significance

Guibi-tang significantly alleviates depressive symptoms in male climacteric depression patients, and BDNF-mediated neuroplasticity enhancement is suggested as the mechanism.

View Source 2023
RCT Men's Health / Urology

Antidepressant Effect of Guibi-tang on Male Climacteric Depression: A Randomized Controlled Trial

곽재현, 문지영, 차승환, et al. Journal of Affective Disorders (2023)
49.3% BDI Score Reduction Rate
82 subjects Number of Subjects
p<0.001 Statistical Significance

Summary

A randomized controlled trial evaluating the antidepressant effect of Guibi-tang in 82 patients with male climacteric depression (BDI ≥14, AMS ≥37). After 12 weeks of administration, BDI scores decreased from an average of 21.3 to 10.8, and serum BDNF levels increased significantly. AMS scores also improved simultaneously.

Key Conclusion

Guibi-tang significantly alleviates depressive symptoms in male climacteric depression patients, and BDNF-mediated neuroplasticity enhancement is suggested as the mechanism.

View Full Paper
Cohort Study Men's Health / Urology

Effect of Acupuncture Treatment on Male Job Stress and Autonomic Nervous System Imbalance: A Cohort Study

한재욱, 신현정, 박용석, et al.

Stress and Health (2024)

28.7% LF/HF Ratio Improvement
104 subjects Cohort Size
8 weeks Treatment Period

Acupuncture treatment effectively corrects autonomic nervous system imbalance due to male job stress and contributes to stress hormone regulation.

View Source 2024
Cohort Study Men's Health / Urology

Effect of Acupuncture Treatment on Male Job Stress and Autonomic Nervous System Imbalance: A Cohort Study

한재욱, 신현정, 박용석, et al. Stress and Health (2024)
28.7% LF/HF Ratio Improvement
104 subjects Cohort Size
8 weeks Treatment Period

Summary

A cohort study analyzing the autonomic nervous system regulation effect of acupuncture treatment in 104 male office workers showing high job stress. After 8 weeks of acupuncture treatment twice weekly, the LF/HF ratio of heart rate variability (HRV) improved significantly, and cortisol awakening response (CAR) also normalized. Job stress scale (KOSS) scores also decreased significantly.

Key Conclusion

Acupuncture treatment effectively corrects autonomic nervous system imbalance due to male job stress and contributes to stress hormone regulation.

View Full Paper