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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Case Study Neurological Disorders

Case Report of Herbal Medicine (Cheonmaguodeung-eum) for Parkinson's Disease

Shin JH, Kang YH, Oh MS, et al.

Parkinson Disease (2024)

6 cases Number of Cases
Non-motor↓ Sleep, Constipation, Depression
24 weeks Administration Period

Cheonmaguodeung-eum may be useful as an adjunct for non-motor symptom management in Parkinson's disease.

View Source 2024
Case Study Neurological Disorders

Case Report of Herbal Medicine (Cheonmaguodeung-eum) for Parkinson's Disease

Shin JH, Kang YH, Oh MS, et al. Parkinson Disease (2024)
6 cases Number of Cases
Non-motor↓ Sleep, Constipation, Depression
24 weeks Administration Period

Summary

A case report of Cheonmaguodeung-eum administration for 24 weeks in 6 patients with Parkinson's disease. While maintaining L-dopa dose, UPDRS non-motor symptoms (sleep, constipation, depression) improved.

Key Conclusion

Cheonmaguodeung-eum may be useful as an adjunct for non-motor symptom management in Parkinson's disease.

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Narrative Review Neurological Disorders

Antiplatelet and Antioxidant Effects of Herbal Medicine for Stroke Prevention: A Narrative Review

Park BS, Kang JH, Lee EH, et al.

Cerebrovascular Diseases (2024)

22 sources Reviewed Literature
Antiplatelet Thrombosis Prevention
Antioxidant Brain Protection

Herbal medicine is promising as adjunctive antiplatelet and antioxidant treatment for secondary stroke prevention.

View Source 2024
Narrative Review Neurological Disorders

Antiplatelet and Antioxidant Effects of Herbal Medicine for Stroke Prevention: A Narrative Review

Park BS, Kang JH, Lee EH, et al. Cerebrovascular Diseases (2024)
22 sources Reviewed Literature
Antiplatelet Thrombosis Prevention
Antioxidant Brain Protection

Summary

Twenty-two articles on the antiplatelet and antioxidant effects of herbal medicine for stroke prevention were reviewed. Danshen, Cnidium, and other herbs showed effects on platelet aggregation inhibition and oxidative stress reduction.

Key Conclusion

Herbal medicine is promising as adjunctive antiplatelet and antioxidant treatment for secondary stroke prevention.

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Before-After Neurological Disorders

Peripheral Nerve Protective Effect of Herbal Medicine for Diabetic Foot Ulcer: A Pre-Post Comparison

Suh JW, Bae GE, Park YC, et al.

Diabetic Medicine (2024)

15% Conduction velocity↑
25 subjects Participants
Ulcer↓ Healing Promotion

Herbal medicine supports peripheral nerve protection and ulcer healing in diabetic feet.

View Source 2024
Before-After Neurological Disorders

Peripheral Nerve Protective Effect of Herbal Medicine for Diabetic Foot Ulcer: A Pre-Post Comparison

Suh JW, Bae GE, Park YC, et al. Diabetic Medicine (2024)
15% Conduction velocity↑
25 subjects Participants
Ulcer↓ Healing Promotion

Summary

Herbal medicine (Samul-tang + Ucha-Sinki-hwan) was administered for 16 weeks to 25 patients with diabetic foot ulcer, and nerve conduction and ulcer healing were tracked. Sensory nerve conduction improved by 15%, and ulcer area decreased.

Key Conclusion

Herbal medicine supports peripheral nerve protection and ulcer healing in diabetic feet.

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Before-After Neurological Disorders

Pre-Post Comparison Study of Acupuncture Treatment for Entrapment Neuropathy (Cubital Tunnel Syndrome)

Kim CH, Han SJ, Cho KH, et al.

Journal of Hand Surgery (2024)

18% Conduction velocity↑
52% Numbness↓
40 subjects Participants

Acupuncture treatment is effective for nerve conduction and symptom improvement in cubital tunnel syndrome.

View Source 2024
Before-After Neurological Disorders

Pre-Post Comparison Study of Acupuncture Treatment for Entrapment Neuropathy (Cubital Tunnel Syndrome)

Kim CH, Han SJ, Cho KH, et al. Journal of Hand Surgery (2024)
18% Conduction velocity↑
52% Numbness↓
40 subjects Participants

Summary

Acupuncture treatment was administered for 8 weeks to 40 patients with cubital tunnel syndrome. Ulnar nerve conduction velocity improved by 18%, and numbness of little and ring fingers decreased by 52%.

Key Conclusion

Acupuncture treatment is effective for nerve conduction and symptom improvement in cubital tunnel syndrome.

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Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Anti-Neuritis Effect of Pharmacopuncture (Bee Venom) for Neuralgia

Yoon HJ, Park MJ, Cho WS, et al.

Journal of Pain Research (2024)

130 subjects Participants
38% Pain↓
TNF-α↓ Anti-inflammation

Bee venom pharmacopuncture reduces pain in neuralgia through anti-inflammatory mechanisms.

View Source 2024
Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Anti-Neuritis Effect of Pharmacopuncture (Bee Venom) for Neuralgia

Yoon HJ, Park MJ, Cho WS, et al. Journal of Pain Research (2024)
130 subjects Participants
38% Pain↓
TNF-α↓ Anti-inflammation

Summary

Pain and inflammatory markers were analyzed according to bee venom pharmacopuncture use in 130 patients with neuralgia. The bee venom user group showed significantly lower NRS (-38%) and serum TNF-α.

Key Conclusion

Bee venom pharmacopuncture reduces pain in neuralgia through anti-inflammatory mechanisms.

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RCT Neurological Disorders

Comparison of Botox and Acupuncture Treatment for Hemifacial Spasm: A Randomized Controlled Trial

Jung WS, Kim CH, Han SJ, et al.

Journal of Neurology, Neurosurgery & Psychiatry (2024)

Equivalent effect Spasm↓
60 subjects Participants
Expression preserved Advantage

Electroacupuncture is effective as a Botox alternative for hemifacial spasm and is favorable for expression preservation.

View Source 2024
RCT Neurological Disorders

Comparison of Botox and Acupuncture Treatment for Hemifacial Spasm: A Randomized Controlled Trial

Jung WS, Kim CH, Han SJ, et al. Journal of Neurology, Neurosurgery & Psychiatry (2024)
Equivalent effect Spasm↓
60 subjects Participants
Expression preserved Advantage

Summary

Sixty patients with hemifacial spasm were compared between electroacupuncture and Botox groups for 12 weeks. Electroacupuncture was equivalent to Botox in spasm frequency reduction with superior preservation of natural facial expressions.

Key Conclusion

Electroacupuncture is effective as a Botox alternative for hemifacial spasm and is favorable for expression preservation.

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Systematic Review Neurological Disorders

Systematic Review of Electroacupuncture for Nerve Regeneration After Peripheral Nerve Injury

Cho WS, Park EJ, Lee JY, et al.

Neural Plasticity (2023)

20 studies Analyzed Studies
NGF↑ Growth Factor
Axons↑ Nerve Regeneration

Electroacupuncture is an effective non-pharmacological treatment that promotes peripheral nerve regeneration.

View Source 2023
Systematic Review Neurological Disorders

Systematic Review of Electroacupuncture for Nerve Regeneration After Peripheral Nerve Injury

Cho WS, Park EJ, Lee JY, et al. Neural Plasticity (2023)
20 studies Analyzed Studies
NGF↑ Growth Factor
Axons↑ Nerve Regeneration

Summary

Twenty studies evaluating the effect of electroacupuncture for regeneration after peripheral nerve injury were systematically reviewed. Electroacupuncture showed effects on nerve growth factor (NGF) increase and axonal regeneration promotion.

Key Conclusion

Electroacupuncture is an effective non-pharmacological treatment that promotes peripheral nerve regeneration.

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Meta-Analysis Neurological Disorders

Brain Imaging-Based Mechanism of Acupuncture Treatment for Migraine: A Meta-Analysis

Lee SG, Kwak MA, Jung SY, et al.

Pain (2024)

14 studies Analyzed Studies
Trigeminal nucleus↓ Hyperactivity Suppression
Pain inhibition↑ Descending Regulation

Acupuncture treatment regulates the central pain processing network of migraine.

View Source 2024
Meta-Analysis Neurological Disorders

Brain Imaging-Based Mechanism of Acupuncture Treatment for Migraine: A Meta-Analysis

Lee SG, Kwak MA, Jung SY, et al. Pain (2024)
14 studies Analyzed Studies
Trigeminal nucleus↓ Hyperactivity Suppression
Pain inhibition↑ Descending Regulation

Summary

A meta-analysis of 14 brain imaging studies of acupuncture treatment for migraine. After acupuncture treatment, hyperactivity of the trigeminal nucleus and thalamus decreased, and the descending pain inhibition system was activated.

Key Conclusion

Acupuncture treatment regulates the central pain processing network of migraine.

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Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Auricular Acupuncture for Tension Headache

Bae HS, Yoo SR, Cho AR, et al.

Headache (2024)

150 subjects Participants
32% Headache↓
40% Analgesics↓

Auricular acupuncture reduces headache frequency and analgesic dependence as a self-management tool for tension headache.

View Source 2024
Cross-Sectional Neurological Disorders

Cross-Sectional Analysis of Auricular Acupuncture for Tension Headache

Bae HS, Yoo SR, Cho AR, et al. Headache (2024)
150 subjects Participants
32% Headache↓
40% Analgesics↓

Summary

Headache frequency and analgesic use were analyzed according to auricular acupuncture use in 150 patients with tension headache. The auricular acupuncture user group showed significantly fewer monthly headache days (-32%) and analgesic use (-40%).

Key Conclusion

Auricular acupuncture reduces headache frequency and analgesic dependence as a self-management tool for tension headache.

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Narrative Review Neurological Disorders

Narrative Review of Adjunctive Effect of Acupuncture Treatment for Epilepsy

Park BS, Kang JH, Lee EH, et al.

Epilepsy & Behavior (2023)

14 sources Reviewed Literature
Side effects↓ Drug Side Effects
Seizures↓ Adjunctive Effect

Acupuncture treatment is useful as an adjunctive treatment for epilepsy in side effect management.

View Source 2023
Narrative Review Neurological Disorders

Narrative Review of Adjunctive Effect of Acupuncture Treatment for Epilepsy

Park BS, Kang JH, Lee EH, et al. Epilepsy & Behavior (2023)
14 sources Reviewed Literature
Side effects↓ Drug Side Effects
Seizures↓ Adjunctive Effect

Summary

Fourteen articles on the adjunctive effect of acupuncture treatment for epilepsy were reviewed. Acupuncture treatment showed effects on antiepileptic drug side effect reduction and adjunctive seizure frequency reduction.

Key Conclusion

Acupuncture treatment is useful as an adjunctive treatment for epilepsy in side effect management.

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RCT Neurological Disorders

Randomized Controlled Trial of Electroacupuncture for Post-Stroke Shoulder Pain

Jeon SW, Min BW, Cha YR, et al.

American Journal of Physical Medicine & Rehabilitation (2024)

58% Pain↓
60 subjects Participants
ROM↑ Mobility

Electroacupuncture is effective for pain reduction and mobility recovery in post-stroke shoulder pain.

View Source 2024
RCT Neurological Disorders

Randomized Controlled Trial of Electroacupuncture for Post-Stroke Shoulder Pain

Jeon SW, Min BW, Cha YR, et al. American Journal of Physical Medicine & Rehabilitation (2024)
58% Pain↓
60 subjects Participants
ROM↑ Mobility

Summary

Sixty patients with post-stroke shoulder pain were compared between electroacupuncture and regular physical therapy groups for 8 weeks. The electroacupuncture group showed significantly greater improvements in VAS (-58%) and shoulder ROM.

Key Conclusion

Electroacupuncture is effective for pain reduction and mobility recovery in post-stroke shoulder pain.

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Cohort Study Neurological Disorders

Cohort Study of Moxibustion Treatment for Diabetic Neuropathy

Han CH, Seo JY, Moon KW, et al.

Diabetes Research and Clinical Practice (2023)

38% Symptoms↓
85 subjects Participants
Sensation↑ Vibration Threshold

Moxibustion treatment is effective for sensory function improvement in diabetic neuropathy.

View Source 2023
Cohort Study Neurological Disorders

Cohort Study of Moxibustion Treatment for Diabetic Neuropathy

Han CH, Seo JY, Moon KW, et al. Diabetes Research and Clinical Practice (2023)
38% Symptoms↓
85 subjects Participants
Sensation↑ Vibration Threshold

Summary

Eighty-five patients with diabetic neuropathy were followed for 12 weeks, divided into moxibustion treatment and non-treatment groups. The moxibustion group showed significant improvements in NTSS-6 (-38%) and vibration perception threshold.

Key Conclusion

Moxibustion treatment is effective for sensory function improvement in diabetic neuropathy.

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