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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Total 93 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al.

Journal of Ethnopharmacology (2023)

80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

View Source 2023
RCT Neurological Disorders

Peripheral Blood Flow Improvement Effect of Danggwisayeokgaosuyusaenggang-tang in Women with Cold Hypersensitivity

Lee EJ, Song YK, Ito S, et al. Journal of Ethnopharmacology (2023)
80 subjects Participants
2.3°C Finger Temperature Rise
p<0.001 Statistical Significance

Summary

Danggwisayeokgaosuyusaenggang-tang was administered for 8 weeks to 80 women complaining of cold hypersensitivity of hands and feet, and peripheral blood flow was evaluated by infrared thermography and laser Doppler. The treatment group showed significant increases in finger skin temperature and blood flow.

Key Conclusion

Danggwisayeokgaosuyusaenggang-tang objectively improves peripheral blood flow in cold hypersensitivity patients.

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Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al.

Otology & Neurotology (2022)

22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

View Source 2022
Meta-Analysis Neurological Disorders

Effect of Acupuncture Treatment for Tinnitus: A Systematic Review and Meta-Analysis

Kim SW, Jung DH, Wang Y, et al. Otology & Neurotology (2022)
22 studies Included Studies
1,856 subjects Total Participants
SMD -0.72 Effect Size

Summary

A meta-analysis of 22 RCTs (total 1,856 subjects) evaluating the effect of acupuncture treatment in tinnitus patients. The acupuncture treatment group showed significant improvement in THI and VAS scores compared with the control group.

Key Conclusion

Acupuncture treatment shows significant effects on symptom severity reduction and quality of life improvement in tinnitus patients.

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RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al.

Cephalalgia (2023)

150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

View Source 2023
RCT Neurological Disorders

Comparison of Effects of Acupuncture Treatment and Regular Analgesics for Tension Headache: An RCT

Choi JY, Baek HJ, Lee MK, et al. Cephalalgia (2023)
150 subjects Participants
62% Headache Days Reduction
8 weeks Treatment Period

Summary

One hundred fifty patients with chronic tension headache were randomly assigned to acupuncture treatment and acetaminophen groups and compared for 8 weeks. The acupuncture treatment group was significantly superior in headache days and VAS scores.

Key Conclusion

Acupuncture treatment is more effective than analgesics for chronic tension headache management with fewer side effects.

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Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al.

BMC Complementary Medicine and Therapies (2024)

120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.

View Source 2024
Cohort Study Neurological Disorders

Effect of Banhabaekchulcheonma-tang on Dizziness: A Prospective Cohort Study

Yoo JH, Nam ES, et al. BMC Complementary Medicine and Therapies (2024)
120 subjects Participants
55% Attack Frequency Reduction
6 months Follow-up Period

Summary

A cohort study following 120 chronic dizziness patients for 6 months, divided into Banhabaekchulcheonma-tang administration and non-administration groups. The herbal medicine administration group showed significant decreases in DHI scores and dizziness attack frequency.

Key Conclusion

Banhabaekchulcheonma-tang can significantly reduce symptom frequency and severity of chronic dizziness.

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Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al.

Journal of Diabetes Research (2023)

25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

View Source 2023
Systematic Review Neurological Disorders

Systematic Review of Korean Medicine Treatment for Diabetic Peripheral Neuropathy

Shin DK, Kim AR, Chen L, et al. Journal of Diabetes Research (2023)
25 studies Included Studies
18 studies Positive Results
Moderate Evidence Level

Summary

Twenty-five studies on Korean medicine treatment (acupuncture, herbal medicine, pharmacopuncture) for diabetic peripheral neuropathy were systematically reviewed. Nerve conduction velocity (NCV) and symptom scores improved in most studies.

Key Conclusion

Korean medicine treatment can be utilized as an adjunctive treatment for symptom relief and nerve function improvement in diabetic peripheral neuropathy.

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Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al.

Journal of Acupuncture and Meridian Studies (2021)

12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

View Source 2021
Case Study Neurological Disorders

Effect of Thread Embedding Therapy for Facial Palsy Sequelae: A Case Series

Han GJ, Park WR, et al. Journal of Acupuncture and Meridian Studies (2021)
12 cases Number of Cases
75% Improvement Rate
3 months Follow-up Period

Summary

A case report of thread embedding therapy in 12 patients with persistent sequelae after facial palsy for more than 6 months. After the procedure, Sunnybrook scores and facial symmetry indices improved.

Key Conclusion

Thread embedding therapy can contribute to facial function and symmetry improvement in patients with chronic facial palsy sequelae.

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RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al.

Evidence-Based Complementary and Alternative Medicine (2022)

100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

View Source 2022
RCT Neurological Disorders

Effect of Moxibustion Treatment for Cold Hypersensitivity: A Randomized Controlled Trial

Kang HW, Lee JA, et al. Evidence-Based Complementary and Alternative Medicine (2022)
100 subjects Participants
3.4 points VAS Reduction
6 weeks Treatment Period

Summary

One hundred patients with cold hypersensitivity of hands and feet were randomly assigned to moxibustion treatment and sham moxibustion groups and compared for 6 weeks. The moxibustion treatment group showed significant improvements in cold sensation VAS and peripheral vascular resistance index.

Key Conclusion

Moxibustion treatment improves both subjective cold sensation and objective blood flow indicators in cold hypersensitivity patients.

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Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al.

International Tinnitus Journal (2024)

180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

View Source 2024
Cohort Study Neurological Disorders

Long-Term Effect of Combined Herbal Medicine-Acupuncture Treatment for Sensorineural Tinnitus: A 2-Year Cohort

Oh SH, Jeon MK, Lee BY, et al. International Tinnitus Journal (2024)
180 subjects Participants
2 years Follow-up Period
43% THI Improvement Rate

Summary

One hundred eighty patients with sensorineural tinnitus were divided into combined herbal medicine-acupuncture treatment and standard treatment groups and followed for 2 years. THI score improvement was greater and more sustained in the combined treatment group.

Key Conclusion

Combined herbal medicine-acupuncture treatment is an effective treatment strategy for long-term management of sensorineural tinnitus.

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Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al.

Headache (2023)

16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

View Source 2023
Meta-Analysis Neurological Disorders

Preventive Effect of Acupuncture Treatment in Migraine Patients: A Meta-Analysis

Lim SH, Chang GT, Yamada K, et al. Headache (2023)
16 studies Included Studies
2,340 subjects Total Participants
-2.8 days Monthly Migraine Reduction

Summary

A meta-analysis of 16 RCTs (total 2,340 subjects) evaluating the effect of acupuncture treatment for migraine prevention. Acupuncture treatment significantly reduced monthly migraine days.

Key Conclusion

Acupuncture treatment is effective for preventive treatment of migraine and can be considered as an alternative to pharmacological prophylaxis.

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Before-After Neurological Disorders

Effect of Korean Medicine Combined Treatment for Benign Paroxysmal Positional Vertigo: A Pre-Post Comparison Study

Seo YM, Cho KH, et al.

Journal of Korean Medicine Rehabilitation (2020)

55 subjects Participants
18% Recurrence Rate Reduction
6 months Follow-up Period

Combined Korean medicine treatment provides additional benefits in symptom improvement and recurrence prevention in BPPV patients.

View Source 2020
Before-After Neurological Disorders

Effect of Korean Medicine Combined Treatment for Benign Paroxysmal Positional Vertigo: A Pre-Post Comparison Study

Seo YM, Cho KH, et al. Journal of Korean Medicine Rehabilitation (2020)
55 subjects Participants
18% Recurrence Rate Reduction
6 months Follow-up Period

Summary

A pre-post comparison study combining canalith repositioning maneuvers with herbal medicine and acupuncture treatment in 55 patients with benign paroxysmal positional vertigo (BPPV). DHI scores and recurrence rates were significantly superior to the canalith repositioning maneuver alone group.

Key Conclusion

Combined Korean medicine treatment provides additional benefits in symptom improvement and recurrence prevention in BPPV patients.

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RCT Neurological Disorders

Effect of Acupuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy: An RCT

Jung WM, Lee HY, Park JH, et al.

JAMA Network Open (2025)

160 subjects Participants
72% Symptom Improvement Rate
12 weeks Treatment Period

Acupuncture treatment is effective for symptom and nerve function improvement in chemotherapy-induced peripheral neuropathy.

View Source 2025
RCT Neurological Disorders

Effect of Acupuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy: An RCT

Jung WM, Lee HY, Park JH, et al. JAMA Network Open (2025)
160 subjects Participants
72% Symptom Improvement Rate
12 weeks Treatment Period

Summary

One hundred sixty cancer patients with chemotherapy-induced peripheral neuropathy were randomly assigned to acupuncture treatment and sham acupuncture groups and compared for 12 weeks. The acupuncture treatment group showed significant improvements in FACT/GOG-Ntx scores and NCV.

Key Conclusion

Acupuncture treatment is effective for symptom and nerve function improvement in chemotherapy-induced peripheral neuropathy.

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Cross-Sectional Neurological Disorders

Correlation Between Cold Hypersensitivity and Autonomic Function: A Korean Medicine Clinical Cross-Sectional Study

Bae GM, Kim NR, et al.

Autonomic Neuroscience (2022)

300 subjects Analysis Subjects
p<0.001 HRV Difference
LF/HF Elevation Sympathetic Hyperactivity

Cold hypersensitivity is closely related to autonomic dysfunction, and Korean medicine autonomic regulation treatment is needed.

View Source 2022
Cross-Sectional Neurological Disorders

Correlation Between Cold Hypersensitivity and Autonomic Function: A Korean Medicine Clinical Cross-Sectional Study

Bae GM, Kim NR, et al. Autonomic Neuroscience (2022)
300 subjects Analysis Subjects
p<0.001 HRV Difference
LF/HF Elevation Sympathetic Hyperactivity

Summary

A cross-sectional study comparing heart rate variability (HRV) and peripheral body temperature in 200 cold hypersensitivity patients and 100 healthy controls. Sympathetic-parasympathetic imbalance was significantly observed in cold hypersensitivity patients.

Key Conclusion

Cold hypersensitivity is closely related to autonomic dysfunction, and Korean medicine autonomic regulation treatment is needed.

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