금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

📅 Book Appointment 📋 Geummaek Herbal Medicine 💬 Reviews 📝 Health Columns
Research Papers
🔍

Total 68 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After Mental Health

Effect of Korean Medicine Combined Treatment on Cortisol and HRV in Chronic Stress Workers

Seo MH, Kim JK, et al.

Stress and Health (2023)

100 subjects Participants
31% Cortisol Reduction
8 weeks Treatment Period

Korean medicine combined treatment effectively regulates physiological and psychological changes due to chronic stress.

View Source 2023
Before-After Mental Health

Effect of Korean Medicine Combined Treatment on Cortisol and HRV in Chronic Stress Workers

Seo MH, Kim JK, et al. Stress and Health (2023)
100 subjects Participants
31% Cortisol Reduction
8 weeks Treatment Period

Summary

Herbal medicine and acupuncture treatment were administered for 8 weeks to 100 workers complaining of chronic stress, and salivary cortisol, HRV, and PSS scores were evaluated. All three indicators improved significantly.

Key Conclusion

Korean medicine combined treatment effectively regulates physiological and psychological changes due to chronic stress.

이 논문 정리 페이지로 이동 →
View Full Paper
Cohort Study Mental Health

Effect of Combined Herbal Medicine-Acupuncture Treatment in Panic Disorder Patients: A Prospective Cohort Study

Park JY, Lee DH, Wang XF, et al.

Neuropsychiatric Disease and Treatment (2024)

90 subjects Participants
68% Attack Frequency Reduction
24 weeks Follow-up Period

Combined herbal medicine-acupuncture treatment shows effects similar to SSRIs in symptom management of panic disorder patients and can be considered as an alternative treatment.

View Source 2024
Cohort Study Mental Health

Effect of Combined Herbal Medicine-Acupuncture Treatment in Panic Disorder Patients: A Prospective Cohort Study

Park JY, Lee DH, Wang XF, et al. Neuropsychiatric Disease and Treatment (2024)
90 subjects Participants
68% Attack Frequency Reduction
24 weeks Follow-up Period

Summary

A prospective cohort study following 90 panic disorder patients for 24 weeks, divided into combined herbal medicine-acupuncture treatment and SSRI alone groups. Panic attack frequency and PDSS scores decreased significantly in the combined treatment group.

Key Conclusion

Combined herbal medicine-acupuncture treatment shows effects similar to SSRIs in symptom management of panic disorder patients and can be considered as an alternative treatment.

이 논문 정리 페이지로 이동 →
View Full Paper
Meta-Analysis Mental Health

Effect of Acupuncture Treatment for Anxiety Disorder: A Systematic Review and Meta-Analysis

Choi SY, Jung WS, Kim YI, et al.

Journal of Clinical Medicine (2023)

20 studies Included Studies
1,680 subjects Total Participants
SMD -0.68 Effect Size

Acupuncture treatment shows significant effects on anxiety symptom relief in generalized anxiety disorder patients.

View Source 2023
Meta-Analysis Mental Health

Effect of Acupuncture Treatment for Anxiety Disorder: A Systematic Review and Meta-Analysis

Choi SY, Jung WS, Kim YI, et al. Journal of Clinical Medicine (2023)
20 studies Included Studies
1,680 subjects Total Participants
SMD -0.68 Effect Size

Summary

A meta-analysis of 20 RCTs (total 1,680 subjects) evaluating the effect of acupuncture treatment in generalized anxiety disorder patients. HAM-A scores decreased significantly in the acupuncture treatment group compared with the control group.

Key Conclusion

Acupuncture treatment shows significant effects on anxiety symptom relief in generalized anxiety disorder patients.

이 논문 정리 페이지로 이동 →
View Full Paper
RCT Mental Health

Antidepressant Effect of Guibi-tang in Mild-to-Moderate Depression Patients: A Double-Blind Randomized Controlled Trial

Kim MJ, Lee SH, Park YC, et al.

Journal of Affective Disorders (2024)

120 subjects Participants
52% HAM-D Response Rate
12 weeks Treatment Period

Guibi-tang is effective for improving depressive symptoms in mild-to-moderate depression patients with few side effects.

View Source 2024
RCT Mental Health

Antidepressant Effect of Guibi-tang in Mild-to-Moderate Depression Patients: A Double-Blind Randomized Controlled Trial

Kim MJ, Lee SH, Park YC, et al. Journal of Affective Disorders (2024)
120 subjects Participants
52% HAM-D Response Rate
12 weeks Treatment Period

Summary

One hundred twenty patients with mild-to-moderate major depressive disorder were double-blind randomly assigned to Guibi-tang and placebo groups and compared for 12 weeks. HAM-D scores decreased significantly in the Guibi-tang group.

Key Conclusion

Guibi-tang is effective for improving depressive symptoms in mild-to-moderate depression patients with few side effects.

이 논문 정리 페이지로 이동 →
View Full Paper
Narrative Review Mental Health

Narrative Review on the Use of Herbal Prescriptions in Mental Health: Focus on Depression and Anxiety Disorders

Park YJ, Chung SY, Kim JW, et al.

Journal of Affective Disorders (2024)

35 sources Analyzed Literature
3 major prescriptions Frequently Used
Mild-moderate efficacy Effect Level

Herbal prescriptions are accumulating evidence as complementary treatment for mild-to-moderate depression and anxiety disorders, with standardization research needed.

View Source 2024
Narrative Review Mental Health

Narrative Review on the Use of Herbal Prescriptions in Mental Health: Focus on Depression and Anxiety Disorders

Park YJ, Chung SY, Kim JW, et al. Journal of Affective Disorders (2024)
35 sources Analyzed Literature
3 major prescriptions Frequently Used
Mild-moderate efficacy Effect Level

Summary

A narrative review of 35 clinical studies addressing the therapeutic effects of herbal prescriptions for depression and anxiety disorders. Prescriptions including Guibi-tang, Soyo-san, and Banhahubak-tang were most frequently studied.

Key Conclusion

Herbal prescriptions are accumulating evidence as complementary treatment for mild-to-moderate depression and anxiety disorders, with standardization research needed.

이 논문 정리 페이지로 이동 →
View Full Paper
Before-After Mental Health

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Panic Disorder Symptom Relief

Chung SY, Kim JH, Park JH, et al.

BMC Complementary Medicine and Therapies (2023)

58% Symptom Severity Reduction
81% Attack Frequency Reduction
56 subjects Study Participants

Korean medicine combined treatment significantly reduces the frequency and severity of panic disorder attacks and can be utilized as an adjunctive treatment strategy to reduce drug dependence.

View Source 2023
Before-After Mental Health

Pre-Post Comparison Study of Korean Medicine Combined Treatment for Panic Disorder Symptom Relief

Chung SY, Kim JH, Park JH, et al. BMC Complementary Medicine and Therapies (2023)
58% Symptom Severity Reduction
81% Attack Frequency Reduction
56 subjects Study Participants

Summary

A pre-post comparison study in which Korean medicine combined treatment combining acupuncture, herbal medicine, and relaxation therapy was administered for 8 weeks to 56 panic disorder patients. PDSS (Panic Disorder Severity Scale) decreased by 58% compared with pre-treatment, and panic attack frequency decreased from 4.2 to 0.8 times per week.

Key Conclusion

Korean medicine combined treatment significantly reduces the frequency and severity of panic disorder attacks and can be utilized as an adjunctive treatment strategy to reduce drug dependence.

이 논문 정리 페이지로 이동 →
View Full Paper
Meta-Analysis Mental Health

Treatment Effect of Acupuncture for Depression: A Systematic Review and Meta-Analysis

Smith CA, Armour M, Lee MS, et al.

Journal of Clinical Medicine (2022)

72% Treatment Response Rate
29 studies Analyzed Studies
2,268 subjects Total Participants

Acupuncture shows significant effects as adjunctive treatment for depression and can contribute to drug side effect reduction and treatment adherence improvement.

View Source 2022
Meta-Analysis Mental Health

Treatment Effect of Acupuncture for Depression: A Systematic Review and Meta-Analysis

Smith CA, Armour M, Lee MS, et al. Journal of Clinical Medicine (2022)
72% Treatment Response Rate
29 studies Analyzed Studies
2,268 subjects Total Participants

Summary

A meta-analysis of 29 randomized controlled trials (total 2,268 subjects) evaluating the depression treatment effect of acupuncture. The acupuncture combined group showed a treatment response rate of 72% based on BDI (Beck Depression Inventory), demonstrating significant differences compared with the drug alone group (58%). The value as an alternative treatment was particularly confirmed in patients with difficulty in drug control due to SSRI side effects.

Key Conclusion

Acupuncture shows significant effects as adjunctive treatment for depression and can contribute to drug side effect reduction and treatment adherence improvement.

이 논문 정리 페이지로 이동 →
View Full Paper
RCT Mental Health

Randomized Controlled Trial of Guibi-tang for Anxiety Disorder Treatment

Park YC, Kim SH, Jo HG, et al.

Journal of Affective Disorders (2023)

52% Anxiety Index Reduction
67% Insomnia Improvement Rate
12 weeks Treatment Period

Guibi-tang shows significant treatment effects on anxiety symptoms and accompanying insomnia in generalized anxiety disorder and also contributes to autonomic balance recovery.

View Source 2023
RCT Mental Health

Randomized Controlled Trial of Guibi-tang for Anxiety Disorder Treatment

Park YC, Kim SH, Jo HG, et al. Journal of Affective Disorders (2023)
52% Anxiety Index Reduction
67% Insomnia Improvement Rate
12 weeks Treatment Period

Summary

A randomized controlled trial comparing 12 weeks of Guibi-tang administration with placebo in 84 generalized anxiety disorder patients. The Guibi-tang group showed an average 52% reduction in HAM-A (Hamilton Anxiety Rating Scale) scores, with 67% improvement rate in accompanying insomnia symptoms. Heart rate variability (HRV) analysis showed significant increase in parasympathetic activity.

Key Conclusion

Guibi-tang shows significant treatment effects on anxiety symptoms and accompanying insomnia in generalized anxiety disorder and also contributes to autonomic balance recovery.

이 논문 정리 페이지로 이동 →
View Full Paper