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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 91 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al.

대한추나의학회지 (2024)

Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

View Source 2024
Case Study Pediatric / Adolescent Care

Case Report of 6 Cases of Combined Chuna Therapy and Herbal Medicine for Pediatric Headache

Gong JH, Im SK, et al. 대한추나의학회지 (2024)
Headache -69.9% Headache frequency reduction
6 cases Number of cases
8 weeks Treatment duration

Summary

A case report on 6 children with chronic headache (tension-type) treated with combined cervical Chuna therapy and modified Cheonung-dajosan. Headache frequency, VAS, and headache diary were analyzed over 8 weeks.

Key Conclusion

After combined Chuna therapy and herbal medicine treatment, headache frequency decreased from an average of 12.3 to 3.7 times per month, and cervical range of motion also significantly improved, confirming the efficacy of cervical Chuna for pediatric headache.

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Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al.

대한한방내과학회지 (2023)

NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

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Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Immune Indicator Changes After Herbal Medicine Treatment in Children with Recurrent Upper Respiratory Tract Infections

Jang HY, Kim WS, et al. 대한한방내과학회지 (2023)
NK +26.3% NK cell activity elevation
CD4/CD8 normalized T-cell ratio improvement
67 patients Study population

Summary

A pre-post comparison over 12 weeks of T-cell subsets (CD4+, CD8+), NK cells, and cytokines (IL-2, IFN-g) before and after modified Bojungikgi-tang administration in 67 children with recurrent upper respiratory tract infections.

Key Conclusion

After modified Bojungikgi-tang treatment, CD4+/CD8+ ratio normalized and NK cell activity and IFN-g levels significantly increased, confirming cellular immune-enhancing effects.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Gut Microbiota Changes After Herbal Medicine Treatment in Children with Anorexia

Jeong DK, Ryu SJ, et al.

대한한방소아과학회지 (2024)

Shannon +0.42 Microbial diversity increase
94 patients Analysis population
Beneficial bacteria +34.5% Beneficial bacteria ratio increase

After herbal medicine treatment, gut microbiota diversity index (Shannon index) significantly increased, and Lactobacillus and Bifidobacterium ratios rose, confirming intestinal environment improvement effects of herbal medicine.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Gut Microbiota Changes After Herbal Medicine Treatment in Children with Anorexia

Jeong DK, Ryu SJ, et al. 대한한방소아과학회지 (2024)
Shannon +0.42 Microbial diversity increase
94 patients Analysis population
Beneficial bacteria +34.5% Beneficial bacteria ratio increase

Summary

A cross-sectional analysis of gut microbiota community (16S rRNA sequencing) changes before and after modified Hyangsayangwi-tang treatment in 94 pediatric patients with anorexia. Microbial diversity index and beneficial bacteria ratios were investigated.

Key Conclusion

After herbal medicine treatment, gut microbiota diversity index (Shannon index) significantly increased, and Lactobacillus and Bifidobacterium ratios rose, confirming intestinal environment improvement effects of herbal medicine.

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Cohort Study Pediatric / Adolescent Care

Cohort Study of Sasang Constitution-Tailored Herbal Medicine Treatment for Pediatric Indigestion

Moon SR, Choi HJ, et al.

대한한방소아과학회지 (2023)

89.8% Overall efficacy rate
167 patients Study population
Soeumin 94.2% Soeumin efficacy rate

Sasang constitution-tailored herbal medicine treatment improved overall efficacy rate to 89.8% in pediatric dyspepsia, with the best results for Insam-yangwi-tang in the Soeumin type.

View Source 2023
Cohort Study Pediatric / Adolescent Care

Cohort Study of Sasang Constitution-Tailored Herbal Medicine Treatment for Pediatric Indigestion

Moon SR, Choi HJ, et al. 대한한방소아과학회지 (2023)
89.8% Overall efficacy rate
167 patients Study population
Soeumin 94.2% Soeumin efficacy rate

Summary

A cohort study following 167 children with functional dyspepsia classified by Sasang constitution for 6 months for constitution-tailored herbal medicine treatment efficacy. Treatment response rates were compared by Soeumin, Soyangin, and Taeumin types.

Key Conclusion

Sasang constitution-tailored herbal medicine treatment improved overall efficacy rate to 89.8% in pediatric dyspepsia, with the best results for Insam-yangwi-tang in the Soeumin type.

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RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Moxibustion for Children with Frequent Colds

Lee CW, Kim HS, et al.

대한한방내과학회지 (2024)

Additional -1.4 episodes Additional cold frequency reduction
88 patients Study population
6 months Follow-up period

The combined herbal medicine and moxibustion group showed an additional 1.4 episodes reduction in cold frequency compared to the herbal medicine alone group, with significantly higher salivary IgA levels, confirming additional immune-enhancing effects of moxibustion.

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RCT Pediatric / Adolescent Care

Randomized Controlled Trial of Combined Herbal Medicine and Moxibustion for Children with Frequent Colds

Lee CW, Kim HS, et al. 대한한방내과학회지 (2024)
Additional -1.4 episodes Additional cold frequency reduction
88 patients Study population
6 months Follow-up period

Summary

An RCT comparing a modified Samso-eum and ST36 moxibustion combination group with an herbal medicine alone group in 88 children with 7 or more colds per year. Cold frequency and immune indicators were followed over 6 months.

Key Conclusion

The combined herbal medicine and moxibustion group showed an additional 1.4 episodes reduction in cold frequency compared to the herbal medicine alone group, with significantly higher salivary IgA levels, confirming additional immune-enhancing effects of moxibustion.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Herbal Medicine Treatment for Boys with Precocious Puberty

Shin YR, Ahn KS, et al.

대한한방소아과학회지 (2024)

Bone age slowing 0.6 years Bone age progression suppression
7 studies Included studies
p<0.01 Statistical significance

Herbal medicine treatment significantly slowed bone age progression in boys with precocious puberty and also showed effects on testosterone level stabilization, presenting potential as adjunctive treatment to GnRH agonists.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Herbal Medicine Treatment for Boys with Precocious Puberty

Shin YR, Ahn KS, et al. 대한한방소아과학회지 (2024)
Bone age slowing 0.6 years Bone age progression suppression
7 studies Included studies
p<0.01 Statistical significance

Summary

A systematic review of herbal medicine (modified Jibaekjihwang-tang, Daebo-eumhwan) treatment efficacy in boys with precocious puberty. Seven studies were analyzed for bone age progression rate, testicular volume, and testosterone levels.

Key Conclusion

Herbal medicine treatment significantly slowed bone age progression in boys with precocious puberty and also showed effects on testosterone level stabilization, presenting potential as adjunctive treatment to GnRH agonists.

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Case Study Pediatric / Adolescent Care

Case Report of 5 Cases of Long-Term Herbal Medicine Treatment for Tourette Syndrome in Children and Adolescents

Bae GH, Yoon CH, et al.

대한한방신경정신과학회지 (2024)

52.8% YGTSS reduction rate
4/5 cases CGI improvement
24 weeks Treatment duration

After 24 weeks of combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 52.8%, and 4 of 5 cases were assessed as much improved or better on CGI, confirming efficacy of long-term treatment.

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Case Study Pediatric / Adolescent Care

Case Report of 5 Cases of Long-Term Herbal Medicine Treatment for Tourette Syndrome in Children and Adolescents

Bae GH, Yoon CH, et al. 대한한방신경정신과학회지 (2024)
52.8% YGTSS reduction rate
4/5 cases CGI improvement
24 weeks Treatment duration

Summary

A long-term follow-up case report on 5 children and adolescents with Tourette syndrome treated with modified Cheonmagudeung-eum and acupuncture (GV20, GB20, LR3) for 24 weeks. YGTSS, CGI, and quality of life were evaluated.

Key Conclusion

After 24 weeks of combined herbal medicine and acupuncture treatment, total YGTSS scores decreased by an average of 52.8%, and 4 of 5 cases were assessed as much improved or better on CGI, confirming efficacy of long-term treatment.

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Cohort Study Pediatric / Adolescent Care

Cohort Study on Effect of Herbal Medicine Treatment for ADHD Children on Academic Concentration

Sung JW, Chae BK, et al.

대한한방신경정신과학회지 (2023)

29.6% CPT error rate reduction
142 patients Study population
6 months Follow-up period

The modified Gwibieondam-tang treatment group showed a 29.6% reduction in CPT error rate and significantly improved response time variability, proving effective for improving academic concentration in children with ADHD.

View Source 2023
Cohort Study Pediatric / Adolescent Care

Cohort Study on Effect of Herbal Medicine Treatment for ADHD Children on Academic Concentration

Sung JW, Chae BK, et al. 대한한방신경정신과학회지 (2023)
29.6% CPT error rate reduction
142 patients Study population
6 months Follow-up period

Summary

A cohort study following 142 children with ADHD for 6 months, comparing a modified Gwibieondam-tang treatment group with a non-treatment group. CPT (Continuous Performance Test), school grades, and teacher behavior assessment were compared.

Key Conclusion

The modified Gwibieondam-tang treatment group showed a 29.6% reduction in CPT error rate and significantly improved response time variability, proving effective for improving academic concentration in children with ADHD.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Winter Herbal Medicine Treatment for Preventing Pediatric Asthma

Yoo KM, Choi JR, et al.

대한한방내과학회지 (2024)

43.8% Acute exacerbation reduction
10 studies Included studies
Hospitalization -37% Hospitalization rate reduction

Winter herbal medicine preventive treatment reduced acute exacerbation of pediatric asthma in winter by 43.8% and significantly lowered emergency room visit and hospitalization rates, presenting evidence for preventive Korean medicine treatment.

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Systematic Review Pediatric / Adolescent Care

Systematic Review of Winter Herbal Medicine Treatment for Preventing Pediatric Asthma

Yoo KM, Choi JR, et al. 대한한방내과학회지 (2024)
43.8% Acute exacerbation reduction
10 studies Included studies
Hospitalization -37% Hospitalization rate reduction

Summary

A systematic review of herbal medicine (Bopyejungcheon-tang, modified Yukgunja-tang) treatment efficacy for preventing winter exacerbation of pediatric asthma. Ten studies were analyzed for winter asthma attack frequency and hospitalization rates.

Key Conclusion

Winter herbal medicine preventive treatment reduced acute exacerbation of pediatric asthma in winter by 43.8% and significantly lowered emergency room visit and hospitalization rates, presenting evidence for preventive Korean medicine treatment.

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Case Study Pediatric / Adolescent Care

Case Report of 8 Pediatric Atopic Dermatitis Cases Treated with Heat-Clearing Herbal Medicine

Lim EH, Go SY, et al.

대한한방안이비인후피부과학회지 (2024)

53.2% EASI reduction rate
8 cases Number of cases
Pruritus -61% Pruritus reduction

After combined oral herbal medicine and topical Jaungo treatment, EASI scores decreased by an average of 53.2% and nocturnal pruritus significantly improved, with concurrent improvement in sleep quality.

View Source 2024
Case Study Pediatric / Adolescent Care

Case Report of 8 Pediatric Atopic Dermatitis Cases Treated with Heat-Clearing Herbal Medicine

Lim EH, Go SY, et al. 대한한방안이비인후피부과학회지 (2024)
53.2% EASI reduction rate
8 cases Number of cases
Pruritus -61% Pruritus reduction

Summary

A case report on 8 children with moderate-to-severe atopic dermatitis treated with modified Hwangryeonhaedok-tang and topical Jaungo. EASI scores, pruritus VAS, and sleep quality were followed over 12 weeks.

Key Conclusion

After combined oral herbal medicine and topical Jaungo treatment, EASI scores decreased by an average of 53.2% and nocturnal pruritus significantly improved, with concurrent improvement in sleep quality.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Herbal Medicine and Acupuncture Treatment for Pediatric Myopia Progression Suppression

Cho HM, Lee WJ, et al.

대한한방안이비인후피부과학회지 (2024)

47.2% Myopia progression suppression rate
173 patients Analysis population
-0.38D/year Annual refractive change

Pediatric myopia patients receiving combined herbal medicine and acupuncture treatment showed annual refractive power change of -0.38D, suppressed by 47.2% compared to untreated group (-0.72D), with significantly reduced axial length elongation rate.

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Cross-Sectional Pediatric / Adolescent Care

Cross-Sectional Analysis of Herbal Medicine and Acupuncture Treatment for Pediatric Myopia Progression Suppression

Cho HM, Lee WJ, et al. 대한한방안이비인후피부과학회지 (2024)
47.2% Myopia progression suppression rate
173 patients Analysis population
-0.38D/year Annual refractive change

Summary

A cross-sectional analysis of medical records from 173 children with myopia progression. Refractive power and axial length changes after modified Gigukjihwang-tang and periocular acupuncture (BL2, ST2, EX-HN5) were investigated.

Key Conclusion

Pediatric myopia patients receiving combined herbal medicine and acupuncture treatment showed annual refractive power change of -0.38D, suppressed by 47.2% compared to untreated group (-0.72D), with significantly reduced axial length elongation rate.

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Case Study Pediatric / Adolescent Care

Case Report of 9 Children with Recurrent Upper Respiratory Tract Infections Treated with Herbal Medicine and Moxibustion

Woo SJ, Lee KH, et al.

대한한방소아과학회지 (2024)

62.5% Infection frequency reduction
71.4% Antibiotic use reduction
9 cases Number of cases

After combined herbal medicine and moxibustion treatment, upper respiratory tract infection frequency decreased by an average of 62.5% and antibiotic use also decreased by 71.4%, confirming the efficacy of Korean medicine treatment in managing recurrent upper respiratory tract infections.

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Case Study Pediatric / Adolescent Care

Case Report of 9 Children with Recurrent Upper Respiratory Tract Infections Treated with Herbal Medicine and Moxibustion

Woo SJ, Lee KH, et al. 대한한방소아과학회지 (2024)
62.5% Infection frequency reduction
71.4% Antibiotic use reduction
9 cases Number of cases

Summary

A case report on 9 children with recurrent upper respiratory tract infections (8 or more per year) treated with modified Samso-eum and moxibustion at GV14 and BL12. Infection frequency and antibiotic use changes were followed over 6 months.

Key Conclusion

After combined herbal medicine and moxibustion treatment, upper respiratory tract infection frequency decreased by an average of 62.5% and antibiotic use also decreased by 71.4%, confirming the efficacy of Korean medicine treatment in managing recurrent upper respiratory tract infections.

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