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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 91 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al.

Pediatric Dermatology (2024)

15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

View Source 2024
Meta-Analysis Pediatric / Adolescent Care

SCORAD Improvement Effect of Herbal Medicine on Pediatric Atopic Dermatitis: A Meta-Analysis

Park JE, Kim SY, Tanaka A, et al. Pediatric Dermatology (2024)
15 studies Included studies
1,240 patients Total participants
WMD -12.4 SCORAD reduction

Summary

Fifteen RCTs (total 1,240 patients) evaluating herbal medicine for pediatric atopic dermatitis were meta-analyzed. The herbal medicine group showed significantly greater SCORAD score reduction compared to controls.

Key Conclusion

Herbal medicine treatment shows significant efficacy in improving SCORAD scores in pediatric atopic dermatitis.

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Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al.

Journal of Ethnopharmacology (2023)

20 studies Included studies
42% Recurrence reduction
High Evidence level

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

View Source 2023
Systematic Review Pediatric / Adolescent Care

Immune-Enhancing Effects of Herbal Medicine on Recurrent Respiratory Infections in Children: A Systematic Review

Lee MH, Cho BK, Wang J, et al. Journal of Ethnopharmacology (2023)
20 studies Included studies
42% Recurrence reduction
High Evidence level

Summary

Twenty studies on herbal medicine (Okbyungpung-san, etc.) for recurrent respiratory infections in children were systematically reviewed. The herbal medicine group showed significant reductions in infection recurrence and antibiotic use.

Key Conclusion

Herbal medicine is an effective complementary therapy for preventing recurrent respiratory infections and enhancing immunity in children.

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RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al.

Pediatrics International (2024)

100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

View Source 2024
RCT Pediatric / Adolescent Care

Growth Hormone Secretion-Promoting Effect of Combination Herbal Medicine on Pediatric Growth Retardation: An RCT

Kim YH, Lee JK, Park SH, et al. Pediatrics International (2024)
100 patients Participants
1.8 cm Growth velocity difference
6 months Treatment duration

Summary

One hundred children with growth retardation were randomly assigned in a double-blind manner to a combination herbal medicine (Seongjang-tang) group or placebo group and compared over 6 months. The herbal medicine group showed significantly higher IGF-1 levels and 6-month growth velocity.

Key Conclusion

Combination herbal medicine promotes growth hormone secretion and improves growth velocity in pediatric growth retardation.

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Before-After Pediatric / Adolescent Care

Effect of Tonic Herbal Prescriptions on Pediatric Growth Disorders: A Pre-Post Comparison Study

Ryoo JY, Kim KB, Min SY, et al.

European Journal of Integrative Medicine (2022)

65 subjects Participants
Annual growth rate 1.8cm increase Growth Promotion
IGF-1 23% increase Growth Hormone Marker

Personalized growth tonic medicine demonstrates positive effects on growth promotion as an adjunctive treatment for pediatric growth disorders.

View Source 2022
Before-After Pediatric / Adolescent Care

Effect of Tonic Herbal Prescriptions on Pediatric Growth Disorders: A Pre-Post Comparison Study

Ryoo JY, Kim KB, Min SY, et al. European Journal of Integrative Medicine (2022)
65 subjects Participants
Annual growth rate 1.8cm increase Growth Promotion
IGF-1 23% increase Growth Hormone Marker

Summary

Sixty-five children with growth retardation received constitution-specific personalized growth tonic medicine for 6 months, and height growth rate and growth hormone-related markers were measured. Annual growth rate significantly increased compared to baseline.

Key Conclusion

Personalized growth tonic medicine demonstrates positive effects on growth promotion as an adjunctive treatment for pediatric growth disorders.

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RCT Pediatric / Adolescent Care

Cognitive Enhancement Effects of Chongmyung-tang on Examinee Concentration

Lee SH, Park HJ, Choi SM, et al.

Journal of Ginseng Research (2023)

23% Memory improvement
18 minutes Concentration time extension
31% Cortisol reduction

Chongmyung-tang significantly improves working memory, concentration, and stress regulation in adolescents, contributing to enhanced learning efficiency.

View Source 2023
RCT Pediatric / Adolescent Care

Cognitive Enhancement Effects of Chongmyung-tang on Examinee Concentration

Lee SH, Park HJ, Choi SM, et al. Journal of Ginseng Research (2023)
23% Memory improvement
18 minutes Concentration time extension
31% Cortisol reduction

Summary

A double-blind RCT comparing 8 weeks of Chongmyung-tang versus placebo in 80 high school students. The Chongmyung-tang group showed a 23% improvement in working memory task accuracy and an 18-minute extension of sustained attention. Cortisol levels decreased by 31%, confirming stress-reduction effects.

Key Conclusion

Chongmyung-tang significantly improves working memory, concentration, and stress regulation in adolescents, contributing to enhanced learning efficiency.

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Systematic Review Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Systematic Review

Bower WF, Diao M, Tang JL, et al.

Neurourology and Urodynamics (2022)

73% Enuresis frequency reduction
52% Complete remission rate
10 studies Analyzed studies

Acupuncture demonstrates significant efficacy in reducing enuresis frequency and achieving complete remission, serving as a safe alternative to pharmacotherapy.

View Source 2022
Systematic Review Pediatric / Adolescent Care

Effect of Acupuncture on Pediatric Enuresis: A Systematic Review

Bower WF, Diao M, Tang JL, et al. Neurourology and Urodynamics (2022)
73% Enuresis frequency reduction
52% Complete remission rate
10 studies Analyzed studies

Summary

Ten RCTs (total 876 patients) evaluating acupuncture for pediatric enuresis were systematically reviewed. Acupuncture reduced enuresis frequency from 5.2 to 1.4 episodes per week (73% reduction), with a complete remission rate of 52%, significantly higher than controls (24%).

Key Conclusion

Acupuncture demonstrates significant efficacy in reducing enuresis frequency and achieving complete remission, serving as a safe alternative to pharmacotherapy.

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RCT Pediatric / Adolescent Care

Effect of Herbal Medicine on Pediatric Growth: A Randomized Controlled Trial

Kim KH, Lee BR, Ryu JH, et al.

Journal of Pediatric Endocrinology and Metabolism (2023)

6.8 cm/year Herbal group growth velocity
28% IGF-1 increase
6 months Treatment duration

Herbal medicine significantly promotes growth velocity in children with short stature, with the mechanism confirmed through the IGF-1 pathway.

View Source 2023
RCT Pediatric / Adolescent Care

Effect of Herbal Medicine on Pediatric Growth: A Randomized Controlled Trial

Kim KH, Lee BR, Ryu JH, et al. Journal of Pediatric Endocrinology and Metabolism (2023)
6.8 cm/year Herbal group growth velocity
28% IGF-1 increase
6 months Treatment duration

Summary

A randomized controlled trial comparing growth-promoting herbal medicine versus placebo over 6 months in 64 children with short stature (ages 6-12). The herbal medicine group showed a mean growth velocity of 6.8 cm/year, significantly higher than placebo (5.1 cm). Serum IGF-1 levels increased by 28%, confirming the growth-promoting mechanism.

Key Conclusion

Herbal medicine significantly promotes growth velocity in children with short stature, with the mechanism confirmed through the IGF-1 pathway.

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