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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 49 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Before-After TMJ Disorder

Stress-Related Symptom Relief Effect of Herbal Medicine (Sosiho-tang) in TMD Patients

Nam DH, Cho SY, Park SU, et al.

BMC Complementary Medicine and Therapies (2023)

60 patients Participants
74% Symptom improvement rate

Sosiho-tang is effective for simultaneously improving mind-body symptoms in stress-related TMD patients.

View Source 2023
Before-After TMJ Disorder

Stress-Related Symptom Relief Effect of Herbal Medicine (Sosiho-tang) in TMD Patients

Nam DH, Cho SY, Park SU, et al. BMC Complementary Medicine and Therapies (2023)
60 patients Participants
74% Symptom improvement rate

Summary

Sosiho-tang was administered for 8 weeks to 60 patients with stress-related TMD. Stress index, TMJ pain, and headache all significantly decreased, with cortisol levels also showing normalization trends.

Key Conclusion

Sosiho-tang is effective for simultaneously improving mind-body symptoms in stress-related TMD patients.

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Cohort Study TMJ Disorder

Cost-Effectiveness Analysis of Korean Medicine Treatment for TMD

Yoon SH, Kim DH, Lee SJ, et al.

Journal of Korean Medicine (2024)

180 patients Participants
18% Medical cost savings

Korean medicine TMD treatment is more cost-effective than Western medicine treatment.

View Source 2024
Cohort Study TMJ Disorder

Cost-Effectiveness Analysis of Korean Medicine Treatment for TMD

Yoon SH, Kim DH, Lee SJ, et al. Journal of Korean Medicine (2024)
180 patients Participants
18% Medical cost savings

Summary

Health insurance claims data of 180 TMD patients were analyzed to compare cost-effectiveness of Korean medicine and Western medicine treatments. Total medical costs in the Korean medicine treatment group were 18% lower, with less additional cost from recurrence.

Key Conclusion

Korean medicine TMD treatment is more cost-effective than Western medicine treatment.

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Cross-Sectional TMJ Disorder

Correlation Between Polysomnography and Korean Medicine Treatment Response in Bruxism Patients

Lim CY, Jang SY, Kwon OH, et al.

Journal of Oral Rehabilitation (2022)

48 patients Participants
r=0.53 Correlation coefficient

Polysomnography findings are useful for predicting Korean medicine treatment response in bruxism patients.

View Source 2022
Cross-Sectional TMJ Disorder

Correlation Between Polysomnography and Korean Medicine Treatment Response in Bruxism Patients

Lim CY, Jang SY, Kwon OH, et al. Journal of Oral Rehabilitation (2022)
48 patients Participants
r=0.53 Correlation coefficient

Summary

Polysomnography findings and Korean medicine treatment (acupuncture, herbal medicine) response were analyzed in 48 patients with nocturnal bruxism. Treatment effects were more pronounced in patients with low sleep efficiency and high arousal index.

Key Conclusion

Polysomnography findings are useful for predicting Korean medicine treatment response in bruxism patients.

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RCT TMJ Disorder

Local Injection Effect of Pharmacopuncture (Anti-Inflammatory Pharmacopuncture) for TMJ Pain: A Randomized Controlled Trial

Ko HJ, Yang JM, Shin BC, et al.

Pain Medicine (2024)

78 patients Participants
81% Pain reduction rate

Local injection of anti-inflammatory pharmacopuncture around the TMJ is an effective treatment for TMD pain.

View Source 2024
RCT TMJ Disorder

Local Injection Effect of Pharmacopuncture (Anti-Inflammatory Pharmacopuncture) for TMJ Pain: A Randomized Controlled Trial

Ko HJ, Yang JM, Shin BC, et al. Pain Medicine (2024)
78 patients Participants
81% Pain reduction rate

Summary

Seventy-eight TMD patients were randomly assigned to anti-inflammatory pharmacopuncture or saline groups, injected around the TMJ. The anti-inflammatory pharmacopuncture group showed significantly superior pain reduction at 2, 4, and 8 weeks.

Key Conclusion

Local injection of anti-inflammatory pharmacopuncture around the TMJ is an effective treatment for TMD pain.

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RCT TMJ Disorder

Brain Functional Changes with Electroacupuncture for TMD: An fMRI Study

Min SB, Hwang EH, Kim KW, et al.

Evidence-Based Complementary and Alternative Medicine (2025)

56 patients Participants
p<0.001 Statistical significance

Electroacupuncture relieves TMD pain by modulating central nervous system pain processing.

View Source 2025
RCT TMJ Disorder

Brain Functional Changes with Electroacupuncture for TMD: An fMRI Study

Min SB, Hwang EH, Kim KW, et al. Evidence-Based Complementary and Alternative Medicine (2025)
56 patients Participants
p<0.001 Statistical significance

Summary

fMRI was performed before and after electroacupuncture in 28 TMD patients and 28 healthy controls. After electroacupuncture, hyperactivity in pain-related brain regions (ACC, insula) significantly decreased.

Key Conclusion

Electroacupuncture relieves TMD pain by modulating central nervous system pain processing.

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Before-After TMJ Disorder

Effect of Chuna Therapy on Occlusal Force Changes in TMD Patients with Malocclusion

Bae GH, Won SY, Cho SH, et al.

Journal of Craniomandibular Practice (2023)

55 patients Participants
38% Occlusal imbalance improvement

Chuna therapy may contribute to recovery of occlusal force balance in TMD patients.

View Source 2023
Before-After TMJ Disorder

Effect of Chuna Therapy on Occlusal Force Changes in TMD Patients with Malocclusion

Bae GH, Won SY, Cho SH, et al. Journal of Craniomandibular Practice (2023)
55 patients Participants
38% Occlusal imbalance improvement

Summary

Chuna therapy was performed for 12 weeks on 55 TMD patients with malocclusion, and occlusal force changes were measured by T-scan. After Chuna therapy, left-right occlusal force imbalance significantly improved.

Key Conclusion

Chuna therapy may contribute to recovery of occlusal force balance in TMD patients.

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Cohort Study TMJ Disorder

Long-Term Korean Medicine Treatment Outcomes in Chronic TMD Patients: A 2-Year Follow-Up Cohort

Jeon SG, Moon SK, Cho KH, et al.

BMC Complementary Medicine and Therapies (2024)

130 patients Participants
41% Recurrence reduction

Korean medicine combination treatment is effective for improving long-term prognosis of chronic TMD patients.

View Source 2024
Cohort Study TMJ Disorder

Long-Term Korean Medicine Treatment Outcomes in Chronic TMD Patients: A 2-Year Follow-Up Cohort

Jeon SG, Moon SK, Cho KH, et al. BMC Complementary Medicine and Therapies (2024)
130 patients Participants
41% Recurrence reduction

Summary

One hundred thirty chronic TMD patients were divided into Korean medicine combination treatment and general conservative treatment groups and followed for 2 years. The Korean medicine treatment group had 41% lower recurrence rates, with significantly superior quality of life scores.

Key Conclusion

Korean medicine combination treatment is effective for improving long-term prognosis of chronic TMD patients.

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Systematic Review TMJ Disorder

Comparison of Acupuncture and Intra-Articular Injection for TMJ Disc Displacement: A Systematic Review

Song JH, Lee KS, Park HM, et al.

Acupuncture in Medicine (2022)

9 studies Included studies
623 patients Total participants

Acupuncture can be a safe alternative to invasive procedures in TMJ disc displacement treatment.

View Source 2022
Systematic Review TMJ Disorder

Comparison of Acupuncture and Intra-Articular Injection for TMJ Disc Displacement: A Systematic Review

Song JH, Lee KS, Park HM, et al. Acupuncture in Medicine (2022)
9 studies Included studies
623 patients Total participants

Summary

Nine studies comparing effects of acupuncture and intra-articular injection (HA, steroid) for TMJ disc displacement were reviewed. Acupuncture showed pain reduction effects equivalent to intra-articular injection while having fewer adverse events.

Key Conclusion

Acupuncture can be a safe alternative to invasive procedures in TMJ disc displacement treatment.

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Before-After TMJ Disorder

Muscle Relaxation and Analgesic Effects of Herbal Medicine (Galgeun-tang) in TMD Patients

Oh JM, Yun YC, Kim BL, et al.

Journal of Korean Medicine (2023)

64 patients Participants
69% Pain reduction rate

Galgeun-tang is an effective herbal medicine prescription for masticatory muscle pain and headache relief related to TMD.

View Source 2023
Before-After TMJ Disorder

Muscle Relaxation and Analgesic Effects of Herbal Medicine (Galgeun-tang) in TMD Patients

Oh JM, Yun YC, Kim BL, et al. Journal of Korean Medicine (2023)
64 patients Participants
69% Pain reduction rate

Summary

Galgeun-tang was administered for 6 weeks to 64 patients with masticatory muscle pain due to TMD. Tenderness thresholds of masseter and temporalis significantly increased, with headache frequency also reduced.

Key Conclusion

Galgeun-tang is an effective herbal medicine prescription for masticatory muscle pain and headache relief related to TMD.

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Meta-Analysis TMJ Disorder

Meta-Analysis of Korean Medicine Treatment for Bruxism/Clenching

Ryu JH, Kim WS, Ahn SH, et al.

Journal of Oral Rehabilitation (2025)

17 studies Included studies
1198 patients Total participants

Korean medicine treatment is effective for comprehensive management of bruxism/clenching and related symptoms.

View Source 2025
Meta-Analysis TMJ Disorder

Meta-Analysis of Korean Medicine Treatment for Bruxism/Clenching

Ryu JH, Kim WS, Ahn SH, et al. Journal of Oral Rehabilitation (2025)
17 studies Included studies
1198 patients Total participants

Summary

Data from 17 studies, 1,198 participants on Korean medicine treatment effects for bruxism/clenching were meta-analyzed. The Korean medicine treatment group showed significant effects compared to controls in bruxism frequency reduction, TMJ pain improvement, and sleep quality enhancement.

Key Conclusion

Korean medicine treatment is effective for comprehensive management of bruxism/clenching and related symptoms.

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RCT TMJ Disorder

Tissue Regeneration Effect of Placenta Pharmacopuncture for TMJ Pain

Kwon KR, Jang JH, Shin MS, et al.

Evidence-Based Complementary and Alternative Medicine (2024)

46 patients Participants
75% Pain reduction rate

Placenta pharmacopuncture contributes to TMD treatment by promoting peri-articular tissue regeneration.

View Source 2024
RCT TMJ Disorder

Tissue Regeneration Effect of Placenta Pharmacopuncture for TMJ Pain

Kwon KR, Jang JH, Shin MS, et al. Evidence-Based Complementary and Alternative Medicine (2024)
46 patients Participants
75% Pain reduction rate

Summary

Forty-six TMD patients were assigned to placenta pharmacopuncture or general pharmacopuncture groups, injected around the TMJ. The placenta pharmacopuncture group showed significantly superior peri-articular tissue improvement on ultrasound and pain reduction.

Key Conclusion

Placenta pharmacopuncture contributes to TMD treatment by promoting peri-articular tissue regeneration.

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RCT TMJ Disorder

Head and Neck Symptom Improvement Effect of Cervical Chuna Therapy in TMD Patients

Yoo DH, Kim TH, Sohn IC, et al.

Journal of Craniomandibular Practice (2024)

68 patients Participants
73% Head/neck symptom improvement

Cervical Chuna therapy is effective for integrative symptom improvement in patients with comorbid TMD and cervical symptoms.

View Source 2024
RCT TMJ Disorder

Head and Neck Symptom Improvement Effect of Cervical Chuna Therapy in TMD Patients

Yoo DH, Kim TH, Sohn IC, et al. Journal of Craniomandibular Practice (2024)
68 patients Participants
73% Head/neck symptom improvement

Summary

Sixty-eight patients with comorbid TMD and cervical dysfunction were assigned to cervical Chuna therapy plus standard treatment or standard treatment alone groups. The Chuna combination group showed significantly more improvements in headache, neck pain, and TMJ pain.

Key Conclusion

Cervical Chuna therapy is effective for integrative symptom improvement in patients with comorbid TMD and cervical symptoms.

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