금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

📅 Book Appointment 📋 Geummaek Herbal Medicine 💬 Reviews 📝 Health Columns
Research Papers
🔍

Total 55 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Systematic Review Wellness / Restoration

Impact of Herbal Tonifying Prescriptions on Sarcopenia Indicators in the Elderly: A Systematic Review

Han SJ, Moon HK, Cho AR, et al.

Aging Clinical and Experimental Research (2024)

16 studies Analyzed papers
Grip strength·walking speed Improvement indicators
Sipjeondaebo-tang Representative prescription

Herbal tonifying prescriptions improve major indicators of elderly sarcopenia, and combination with exercise therapy is recommended.

View Source 2024
Systematic Review Wellness / Restoration

Impact of Herbal Tonifying Prescriptions on Sarcopenia Indicators in the Elderly: A Systematic Review

Han SJ, Moon HK, Cho AR, et al. Aging Clinical and Experimental Research (2024)
16 studies Analyzed papers
Grip strength·walking speed Improvement indicators
Sipjeondaebo-tang Representative prescription

Summary

Sixteen studies on effects of herbal tonifying prescriptions (Sipjeondaebo-tang, Bojungikgi-tang, etc.) for elderly sarcopenia were systematically reviewed. Grip strength, walking speed, and skeletal muscle mass index significantly improved in the herbal medicine administration group.

Key Conclusion

Herbal tonifying prescriptions improve major indicators of elderly sarcopenia, and combination with exercise therapy is recommended.

View Full Paper
RCT Wellness / Restoration

Effect of Sasang Constitution-Tailored Yangsaeng Methods on Quality of Life: A Randomized Controlled Trial

Jang ES, Baek YH, Kim KY, et al.

BMC Complementary Medicine and Therapies (2023)

22 points SF-36 improvement
200 patients Participants
24 weeks Observation period

Sasang constitution-tailored yangsaeng methods have significant effects on quality of life improvement as personalized health management.

View Source 2023
RCT Wellness / Restoration

Effect of Sasang Constitution-Tailored Yangsaeng Methods on Quality of Life: A Randomized Controlled Trial

Jang ES, Baek YH, Kim KY, et al. BMC Complementary Medicine and Therapies (2023)
22 points SF-36 improvement
200 patients Participants
24 weeks Observation period

Summary

Two hundred healthy adults were divided into Sasang constitution-tailored yangsaeng method and general health management groups and compared over 24 weeks. The tailored group showed an average 22-point improvement in SF-36 quality of life scores, with the greatest improvement particularly in the vitality domain.

Key Conclusion

Sasang constitution-tailored yangsaeng methods have significant effects on quality of life improvement as personalized health management.

View Full Paper
Meta-Analysis Wellness / Restoration

Autonomic Nervous System Modulation Effect of Acupuncture and Heart Rate Variability Analysis: A Meta-Analysis

Bae JH, Kwon CY, Lee BH, et al.

Autonomic Neuroscience (2024)

28 studies Analyzed papers
HF increase Parasympathetic activity
LF/HF improvement Autonomic balance

Acupuncture increases parasympathetic activity and restores autonomic balance, being effective for managing stress-related diseases.

View Source 2024
Meta-Analysis Wellness / Restoration

Autonomic Nervous System Modulation Effect of Acupuncture and Heart Rate Variability Analysis: A Meta-Analysis

Bae JH, Kwon CY, Lee BH, et al. Autonomic Neuroscience (2024)
28 studies Analyzed papers
HF increase Parasympathetic activity
LF/HF improvement Autonomic balance

Summary

Twenty-eight studies evaluating the impact of acupuncture on the autonomic nervous system using heart rate variability (HRV) were meta-analyzed. After acupuncture, parasympathetic activity indicator (HF) significantly increased, with improved sympathetic/parasympathetic balance (LF/HF ratio).

Key Conclusion

Acupuncture increases parasympathetic activity and restores autonomic balance, being effective for managing stress-related diseases.

View Full Paper
Cohort Study Wellness / Restoration

Impact of Yakseon Dietary Therapy on Metabolic Syndrome Risk Factors: A Cohort Study

Yoo TW, Shin MK, Lee JA, et al.

Nutrition Research and Practice (2023)

-4.2 cm Waist circumference reduction
-28% Triglyceride reduction
160 patients Participants

Yakseon dietary therapy effectively improves metabolic syndrome risk factors and is useful for preventive health management.

View Source 2023
Cohort Study Wellness / Restoration

Impact of Yakseon Dietary Therapy on Metabolic Syndrome Risk Factors: A Cohort Study

Yoo TW, Shin MK, Lee JA, et al. Nutrition Research and Practice (2023)
-4.2 cm Waist circumference reduction
-28% Triglyceride reduction
160 patients Participants

Summary

One hundred sixty adults with prediabetes were divided into yakseon dietary therapy and general dietary groups and followed for 16 weeks. The yakseon group showed significant decreases in waist circumference (-4.2 cm), triglycerides (-28%), and fasting blood glucose (-12 mg/dL).

Key Conclusion

Yakseon dietary therapy effectively improves metabolic syndrome risk factors and is useful for preventive health management.

View Full Paper
RCT Wellness / Restoration

Effect of Doin Exercise on Physical Strength and Mental Health in Middle-Aged Adults: A Randomized Controlled Trial

Ahn TW, Go HY, Nam DH, et al.

Journal of Exercise Rehabilitation (2024)

34% Flexibility improvement
42% Depression symptom reduction
90 patients Participants

Doin exercise shows effects equivalent or superior to aerobic exercise on physical strength enhancement and mental health improvement in middle-aged adults.

View Source 2024
RCT Wellness / Restoration

Effect of Doin Exercise on Physical Strength and Mental Health in Middle-Aged Adults: A Randomized Controlled Trial

Ahn TW, Go HY, Nam DH, et al. Journal of Exercise Rehabilitation (2024)
34% Flexibility improvement
42% Depression symptom reduction
90 patients Participants

Summary

Ninety adults aged 40-60 were divided into Doin exercise, aerobic exercise, and non-exercise control groups and compared over 12 weeks. The Doin exercise group showed the greatest improvements in flexibility (34% improvement), balance (sit-to-stand 28% improvement), and PHQ-9 depression scores (-42%).

Key Conclusion

Doin exercise shows effects equivalent or superior to aerobic exercise on physical strength enhancement and mental health improvement in middle-aged adults.

View Full Paper
Meta-Analysis Wellness / Restoration

Systematic Review and Meta-Analysis of Immune Modulation Effects of Bojungikgi-tang

Choi JH, Lee AR, Park SY, et al.

Phytomedicine (2023)

24 studies Analyzed papers
NK cell increase Innate immunity enhancement
CD4/CD8 improvement Adaptive immunity modulation

Bojungikgi-tang shows significant immune enhancement effects on both innate and adaptive immunity, and is effective for patients with immune decline.

View Source 2023
Meta-Analysis Wellness / Restoration

Systematic Review and Meta-Analysis of Immune Modulation Effects of Bojungikgi-tang

Choi JH, Lee AR, Park SY, et al. Phytomedicine (2023)
24 studies Analyzed papers
NK cell increase Innate immunity enhancement
CD4/CD8 improvement Adaptive immunity modulation

Summary

Twenty-four studies evaluating immune modulation effects of Bojungikgi-tang were meta-analyzed. NK cell activity increase (SMD: 0.82), CD4/CD8 ratio improvement (SMD: 0.56), and IgA level elevation (SMD: 0.71) were confirmed.

Key Conclusion

Bojungikgi-tang shows significant immune enhancement effects on both innate and adaptive immunity, and is effective for patients with immune decline.

View Full Paper
Cohort Study Wellness / Restoration

Impact of Four Seasons Yangsaeng Method Program on Health Indicators in Chronic Disease Patients: A 1-Year Cohort Study

Park BS, Jeon SW, Kim DI, et al.

Preventive Medicine (2023)

45% ER visit reduction
240 patients Participants
1 year Follow-up period

Four seasons yangsaeng methods complement chronic disease management, reducing medical utilization and improving self-management capacity.

View Source 2023
Cohort Study Wellness / Restoration

Impact of Four Seasons Yangsaeng Method Program on Health Indicators in Chronic Disease Patients: A 1-Year Cohort Study

Park BS, Jeon SW, Kim DI, et al. Preventive Medicine (2023)
45% ER visit reduction
240 patients Participants
1 year Follow-up period

Summary

Seasonal customized yangsaeng programs were applied for 1 year to 240 chronic disease (hypertension, diabetes, hyperlipidemia) patients, and health indicators were tracked. The program participation group showed improvements in emergency room visits (-45%), medication dose adjustments (-22%), and health self-efficacy (+38%).

Key Conclusion

Four seasons yangsaeng methods complement chronic disease management, reducing medical utilization and improving self-management capacity.

View Full Paper
Cross-Sectional Wellness / Restoration

Impact of Moxibustion Treatment on Immunoglobulin Levels and Inflammation Markers: A Cross-Sectional Analysis

Kwak MA, Suh JW, Han JM, et al.

Journal of Immunology Research (2024)

280 patients Total participants
IgA increase Mucosal immunity enhancement
hs-CRP reduction Inflammation suppression

Regular moxibustion treatment has effects on strengthening mucosal immunity (IgA) and suppressing chronic low-grade inflammation.

View Source 2024
Cross-Sectional Wellness / Restoration

Impact of Moxibustion Treatment on Immunoglobulin Levels and Inflammation Markers: A Cross-Sectional Analysis

Kwak MA, Suh JW, Han JM, et al. Journal of Immunology Research (2024)
280 patients Total participants
IgA increase Mucosal immunity enhancement
hs-CRP reduction Inflammation suppression

Summary

Immunoglobulins (IgG, IgA, IgM) and inflammation markers (hs-CRP, ESR) were compared between regular moxibustion users (130) and non-users (150) among health check-up subjects. The moxibustion users showed significantly higher IgA and lower hs-CRP.

Key Conclusion

Regular moxibustion treatment has effects on strengthening mucosal immunity (IgA) and suppressing chronic low-grade inflammation.

View Full Paper
Before-After Wellness / Restoration

Effect of Korean Medicine Detoxification Program on Heavy Metal Excretion: A Pre-Post Comparison Study

Chung SH, Lee HJ, Yoo SR, et al.

Environmental Health and Preventive Medicine (2023)

32% Mercury reduction
18% Lead reduction
60 patients Participants

Korean medicine detoxification program promotes heavy metal excretion from the body and is useful for health management of modern people with high environmental pollution exposure.

View Source 2023
Before-After Wellness / Restoration

Effect of Korean Medicine Detoxification Program on Heavy Metal Excretion: A Pre-Post Comparison Study

Chung SH, Lee HJ, Yoo SR, et al. Environmental Health and Preventive Medicine (2023)
32% Mercury reduction
18% Lead reduction
60 patients Participants

Summary

Korean medicine detoxification program (mung bean drink, acupuncture, sweat therapy) was applied for 6 weeks to 60 adults with high body heavy metal (mercury, lead, cadmium) levels. Blood mercury (-32%), lead (-18%), and urine cadmium (-25%) significantly decreased.

Key Conclusion

Korean medicine detoxification program promotes heavy metal excretion from the body and is useful for health management of modern people with high environmental pollution exposure.

View Full Paper
Narrative Review Wellness / Restoration

Effect of Qigong Practice on Stress Hormones and Telomere Length: A Narrative Review

Shin JH, Oh MS, Park JK, et al.

Journal of Integrative Medicine (2023)

28 studies Reviewed papers
Telomere Anti-aging biomarker
Cortisol reduction Stress regulation

Qigong practice can delay cellular aging through stress hormone regulation and telomere maintenance.

View Source 2023
Narrative Review Wellness / Restoration

Effect of Qigong Practice on Stress Hormones and Telomere Length: A Narrative Review

Shin JH, Oh MS, Park JK, et al. Journal of Integrative Medicine (2023)
28 studies Reviewed papers
Telomere Anti-aging biomarker
Cortisol reduction Stress regulation

Summary

Twenty-eight papers on anti-aging effects of qigong practice were narratively reviewed. Regular qigong practice was associated with cortisol reduction, DHEA-S increase, and telomere length maintenance, suggesting potential for cellular aging delay.

Key Conclusion

Qigong practice can delay cellular aging through stress hormone regulation and telomere maintenance.

View Full Paper
Cross-Sectional Wellness / Restoration

Disease Prediction Accuracy of Korean Medicine Constitution-Tailored Health Examination: A Cross-Sectional Analysis

Go JH, Lee SY, Bae HS, et al.

BMJ Open (2023)

500 patients Participants
AUC +0.12 Predictive accuracy improvement
5 years Follow-up period

Sasang constitution-based health examination has higher disease prediction accuracy compared to standard examination and can be utilized as a tool for personalized preventive medicine.

View Source 2023
Cross-Sectional Wellness / Restoration

Disease Prediction Accuracy of Korean Medicine Constitution-Tailored Health Examination: A Cross-Sectional Analysis

Go JH, Lee SY, Bae HS, et al. BMJ Open (2023)
500 patients Participants
AUC +0.12 Predictive accuracy improvement
5 years Follow-up period

Summary

Five-year disease occurrence prediction accuracy of Sasang constitution diagnosis-based health examination and standard health examination was compared in 500 health check-up subjects. AUC of constitution-tailored examination was 0.12 higher than standard examination, with particularly large differences in metabolic disease prediction.

Key Conclusion

Sasang constitution-based health examination has higher disease prediction accuracy compared to standard examination and can be utilized as a tool for personalized preventive medicine.

View Full Paper
Cross-Sectional Wellness / Restoration

Correlation Between Korean Medicine Yangsaeng Practice and Healthy Lifespan in Longevity Region Elderly: A Multi-Region Cross-Sectional Study

Kang SH, Lee JM, Park DH, et al.

Archives of Gerontology and Geriatrics (2023)

420 patients Participants
4.7 years Healthy lifespan difference
3 regions Multi-region study

Korean medicine yangsaeng practice shows significant correlation with healthy lifespan extension in the elderly.

View Source 2023
Cross-Sectional Wellness / Restoration

Correlation Between Korean Medicine Yangsaeng Practice and Healthy Lifespan in Longevity Region Elderly: A Multi-Region Cross-Sectional Study

Kang SH, Lee JM, Park DH, et al. Archives of Gerontology and Geriatrics (2023)
420 patients Participants
4.7 years Healthy lifespan difference
3 regions Multi-region study

Summary

Levels of Korean medicine yangsaeng practice (diet, exercise, sleep, emotion management) and healthy lifespan indicators were analyzed in 420 elderly from 3 Korean longevity belt regions. The top 25% yangsaeng practice score group had an average 4.7 years longer ADL independence period than the bottom 25%.

Key Conclusion

Korean medicine yangsaeng practice shows significant correlation with healthy lifespan extension in the elderly.

View Full Paper