금맥한의원
Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

Research Papers
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Total 55 papers

Narrative Review Wellness / Restoration

Modern Interpretation and Health Promotion Application of Korean Medicine Yangsaeng Methods: A Narrative Review

Jung WS, Moon SK, Ko CN, et al.

BMC Complementary Medicine and Therapies (2021)

N/A Review study
50 studies Analyzed papers

Korean medicine yangsaeng methods can be the foundation for modern preventive medicine and integrative health management.

Narrative Review Wellness / Restoration

Modern Interpretation and Health Promotion Application of Korean Medicine Yangsaeng Methods: A Narrative Review

Jung WS, Moon SK, Ko CN, et al. BMC Complementary Medicine and Therapies (2021)
N/A Review study
50 studies Analyzed papers

Summary

A narrative review reinterpreting traditional yangsaeng methods of Korean medicine classics from a modern health promotion perspective. Scientific evidence and modern application methods of traditional yangsaeng principles including diet, exercise, mental cultivation, and seasonal yangsaeng were organized.

Key Conclusion

Korean medicine yangsaeng methods can be the foundation for modern preventive medicine and integrative health management.

Systematic Review Wellness / Restoration

Systematic Review of Hepatoprotective Effects of Tonifying Herbal Medicine

Seo BK, Han CH, Choi JB, et al.

Journal of Ethnopharmacology (2024)

27% Liver enzyme improvement rate
980 patients Total participants

Tonifying herbal medicine is effective for hepatoprotection and can be utilized for liver disease prevention.

Systematic Review Wellness / Restoration

Systematic Review of Hepatoprotective Effects of Tonifying Herbal Medicine

Seo BK, Han CH, Choi JB, et al. Journal of Ethnopharmacology (2024)
27% Liver enzyme improvement rate
980 patients Total participants

Summary

A systematic review evaluating hepatoprotective effects of tonifying herbal medicine. Analysis of 15 studies showed significant improvements in liver enzyme levels and hepatocyte protective effects in the tonifying herbal medicine administration group.

Key Conclusion

Tonifying herbal medicine is effective for hepatoprotection and can be utilized for liver disease prevention.

Before-After Wellness / Restoration

Immune-Enhancing and Autonomic Nervous System Modulation Effects of Moxibustion: A Pre-Post Comparison Study

Oh MS, Kang JW, Lee HJ, et al.

Evidence-Based Complementary and Alternative Medicine (2023)

32% NK cell activity increase
45 patients Participants

Moxibustion is an effective Korean medicine tonifying treatment for immune enhancement and autonomic balance recovery.

Before-After Wellness / Restoration

Immune-Enhancing and Autonomic Nervous System Modulation Effects of Moxibustion: A Pre-Post Comparison Study

Oh MS, Kang JW, Lee HJ, et al. Evidence-Based Complementary and Alternative Medicine (2023)
32% NK cell activity increase
45 patients Participants

Summary

Moxibustion at CV4 and ST36 was performed for 8 weeks in 45 adults complaining of immune decline, with pre-post comparison of immune indicators and autonomic function. NK cell activity and parasympathetic activity significantly increased.

Key Conclusion

Moxibustion is an effective Korean medicine tonifying treatment for immune enhancement and autonomic balance recovery.

Cohort Study Wellness / Restoration

Changes in Health Indicators After Korean Medicine Tonifying Treatment in Chronic Disease Patients: A Prospective Cohort Study

Yang CS, Kwon SJ, Park HJ, et al.

BMC Complementary Medicine and Therapies (2025)

40% Health indicator improvement rate
90 patients Participants

Korean medicine tonifying treatment contributes to health indicator improvement and overall health status enhancement in chronic disease patients.

Cohort Study Wellness / Restoration

Changes in Health Indicators After Korean Medicine Tonifying Treatment in Chronic Disease Patients: A Prospective Cohort Study

Yang CS, Kwon SJ, Park HJ, et al. BMC Complementary Medicine and Therapies (2025)
40% Health indicator improvement rate
90 patients Participants

Summary

A prospective cohort study combining Korean medicine tonifying treatment for 6 months and tracking health indicators in 90 patients with chronic diseases (hypertension, diabetes). Improvements appeared in blood pressure, blood glucose, body mass index, and fatigue.

Key Conclusion

Korean medicine tonifying treatment contributes to health indicator improvement and overall health status enhancement in chronic disease patients.

Meta-Analysis Wellness / Restoration

Meta-Analysis of Sarcopenia Prevention Effect of Herbal Tonifying Prescriptions

Jang SB, Lee JA, Shin YC, et al.

Journal of Ethnopharmacology (2025)

19% Muscle strength improvement rate
480 patients Total participants

Tonifying herbal medicine is effective for sarcopenia prevention and may contribute to extending healthy lifespan in the elderly.

Meta-Analysis Wellness / Restoration

Meta-Analysis of Sarcopenia Prevention Effect of Herbal Tonifying Prescriptions

Jang SB, Lee JA, Shin YC, et al. Journal of Ethnopharmacology (2025)
19% Muscle strength improvement rate
480 patients Total participants

Summary

A meta-analysis evaluating sarcopenia prevention effects of herbal tonifying prescriptions. Analysis of 8 studies showed significant improvements in muscle mass, muscle strength, and walking speed in the tonifying herbal medicine administration group.

Key Conclusion

Tonifying herbal medicine is effective for sarcopenia prevention and may contribute to extending healthy lifespan in the elderly.

Systematic Review Wellness / Restoration

Systematic Review and Meta-Analysis of Hepatotoxicity Risk in Herbal Medicine Treatment

Park MJ, Seo JH, Kim DH et al.

BMC Complementary Medicine and Therapies (2023)

15,847 subjects Subjects Analyzed
0.28% Liver Abnormality Incidence
1/3-1/5 level vs Western Medicine

The incidence of liver function abnormalities with herbal medicine prescribed by qualified Korean medicine doctors was 0.28%, significantly lower than conventional pharmaceuticals (0.7-1.4%). Concerns about hepatotoxicity from herbal medicine are overestimated.

2023
Systematic Review Wellness / Restoration

Systematic Review and Meta-Analysis of Hepatotoxicity Risk in Herbal Medicine Treatment

Park MJ, Seo JH, Kim DH et al. BMC Complementary Medicine and Therapies (2023)
15,847 subjects Subjects Analyzed
0.28% Liver Abnormality Incidence
1/3-1/5 level vs Western Medicine

Summary

Meta-analysis of 45 studies (total 15,847 subjects) published from 2010-2023 on the incidence of liver function abnormalities during herbal medicine treatment.

Key Conclusion

The incidence of liver function abnormalities with herbal medicine prescribed by qualified Korean medicine doctors was 0.28%, significantly lower than conventional pharmaceuticals (0.7-1.4%). Concerns about hepatotoxicity from herbal medicine are overestimated.

Narrative Review Wellness / Restoration

Comparative Study of Active Component Extraction Rates by Herbal Decoction Temperature

Hwang JY, Bae KH, Song YR et al.

생약학회지 (2024)

+34% Glycoside Preservation Rate
+52% Essential Oil Preservation
+21% Total Efficacy Markers

Low-temperature extraction at 85°C preserved heat-sensitive glycosides and essential oil components an average of 34% more than high-temperature extraction at 100°C, with significantly superior total efficacy marker components.

2024
Narrative Review Wellness / Restoration

Comparative Study of Active Component Extraction Rates by Herbal Decoction Temperature

Hwang JY, Bae KH, Song YR et al. 생약학회지 (2024)
+34% Glycoside Preservation Rate
+52% Essential Oil Preservation
+21% Total Efficacy Markers

Summary

Active component contents of 20 major medicinal herbs were comparatively analyzed by HPLC under 70°C, 85°C, and 100°C extraction conditions.

Key Conclusion

Low-temperature extraction at 85°C preserved heat-sensitive glycosides and essential oil components an average of 34% more than high-temperature extraction at 100°C, with significantly superior total efficacy marker components.