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Geummaek Research

Research Papers

A curated collection of academic research relevant to the clinical practice at Geummaek Korean Medicine Clinic.

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Research Papers
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Total 1642 papers

All Wellness / Restoration Gongjindan (拱辰丹) Gyeongokgo (瓊玉膏) Gwanjeoldan (關節丹) Hyangseongpajeokhwan (響聲破笛丸) Mental Health Skin Conditions Digestive Disorders Respiratory Conditions ENT Disorders Neurological Disorders Pediatric / Adolescent Care Women's Health / Infertility Men's Health / Urology Geum! Maek! Capsule Diet Geum! Maek! Beauty Clinic Private Inpatient Room Traffic Accident Aftercare Pediatric Traffic Accident Workers' Compensation Lower Back Pain Neck Pain Shoulder Pain Elbow Pain Wrist / Hand Pain Hip Pain Knee Pain Ankle / Foot Pain TMJ Disorder
Cohort Study Respiratory Conditions

Herbal Medicine Preventive Effect on Respiratory Symptoms in Residents of Particulate Matter Exposure Areas: A Cohort Study

박세진, 김하윤, 이병규, et al.

대한예방한의학회지 (2023)

28 days Symptom days reduction
214 patients Study population
12 months Follow-up period

Intermittent herbal medicine administration is an effective preventive strategy for respiratory health protection in residents of high particulate matter exposure areas.

View Source 2023
Cohort Study Respiratory Conditions

Herbal Medicine Preventive Effect on Respiratory Symptoms in Residents of Particulate Matter Exposure Areas: A Cohort Study

박세진, 김하윤, 이병규, et al. 대한예방한의학회지 (2023)
28 days Symptom days reduction
214 patients Study population
12 months Follow-up period

Summary

A cohort study following 214 adults residing in areas with high annual average particulate matter concentration for 12 months, comparing intermittent 4-week Cheongpyesagan-tang administration versus non-administration. The herbal medicine group showed average 28-day annual reduction in respiratory symptom days, with attenuated pulmonary function decline rate.

Key Conclusion

Intermittent herbal medicine administration is an effective preventive strategy for respiratory health protection in residents of high particulate matter exposure areas.

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Case Study ENT Disorders

Effect of Combined Acupuncture and Herbal Medicine for Long COVID Olfactory Disorder: A Case Report of 8 Cases

김주현, 박다은, 이정빈, et al.

대한침구의학회지 (2024)

62% UPSIT score improvement
8 patients Number of cases
75% Normal recovery rate

Combined acupuncture and herbal medicine promotes recovery of long COVID olfactory disorder and can be utilized as complementary treatment for olfactory rehabilitation.

View Source 2024
Case Study ENT Disorders

Effect of Combined Acupuncture and Herbal Medicine for Long COVID Olfactory Disorder: A Case Report of 8 Cases

김주현, 박다은, 이정빈, et al. 대한침구의학회지 (2024)
62% UPSIT score improvement
8 patients Number of cases
75% Normal recovery rate

Summary

A case report combining acupuncture at LI20, Bitong, LI4 with modified Bojungikgi-tang for 10 weeks in 8 patients with olfactory decline/anosmia persisting more than 3 months after COVID-19 infection. UPSIT (olfactory test) scores improved by an average of 62% compared to before treatment, with 6 patients showing recovery within normal range.

Key Conclusion

Combined acupuncture and herbal medicine promotes recovery of long COVID olfactory disorder and can be utilized as complementary treatment for olfactory rehabilitation.

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Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment for Acute Bronchitis: Antibiotic Combination vs. Herbal Medicine Alone

정현우, 김선아, 박영준, et al.

Frontiers in Pharmacology (2023)

11 studies Analyzed studies
924 patients Total study population
Non-inferior Herbal medicine alone effect

Herbal medicine shows effective treatment results as monotherapy without antibiotics in mild acute bronchitis and may contribute to appropriate antibiotic use.

View Source 2023
Meta-Analysis Respiratory Conditions

Meta-Analysis of Herbal Medicine Treatment for Acute Bronchitis: Antibiotic Combination vs. Herbal Medicine Alone

정현우, 김선아, 박영준, et al. Frontiers in Pharmacology (2023)
11 studies Analyzed studies
924 patients Total study population
Non-inferior Herbal medicine alone effect

Summary

A meta-analysis of 11 RCTs (total 924 patients) analyzing herbal medicine treatment for acute bronchitis divided into antibiotic combination and herbal medicine alone groups. Both groups showed significant symptom improvement, with the herbal medicine alone group showing non-inferior cough resolution rate to the antibiotic combination group.

Key Conclusion

Herbal medicine shows effective treatment results as monotherapy without antibiotics in mild acute bronchitis and may contribute to appropriate antibiotic use.

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Case Study Men's Health / Urology

Effect of Herbal Medicine Treatment for Hydrocele: A Multicenter Case Report

임현준, 강유진, 배동식, et al.

대한한방내과학회지 (2023)

47.2% Hydrocele Reduction Rate
15 cases Number of Cases
13.3% 12-month Recurrence Rate

Herbal medicine treatment is effective as a non-surgical treatment alternative for mild-to-moderate hydrocele and shows lower recurrence rates compared with surgery.

View Source 2023
Case Study Men's Health / Urology

Effect of Herbal Medicine Treatment for Hydrocele: A Multicenter Case Report

임현준, 강유진, 배동식, et al. 대한한방내과학회지 (2023)
47.2% Hydrocele Reduction Rate
15 cases Number of Cases
13.3% 12-month Recurrence Rate

Summary

A multicenter case report on herbal medicine treatment in 15 patients with hydrocele. After 8-12 weeks of administration of modified Oryeong-san or modified Danggwijakyak-san at 3 Korean medicine hospitals, hydrocele volume on ultrasound decreased by an average of 47.2%, and complete resolution was confirmed in 4 patients. Recurrence rate at 12-month follow-up was 13.3%.

Key Conclusion

Herbal medicine treatment is effective as a non-surgical treatment alternative for mild-to-moderate hydrocele and shows lower recurrence rates compared with surgery.

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Meta-Analysis Men's Health / Urology

Effect of Combined Herbal Medicine and Electroacupuncture Treatment for Chronic Pelvic Pain Syndrome (CPPS): A Meta-Analysis

윤정호, 김상민, 이동현, et al.

Prostate (2024)

12.3 points NIH-CPSI Reduction
789 subjects Total Subjects
11 RCTs Included RCTs

Combined herbal medicine and electroacupuncture treatment is effective across all pain, urinary, and quality of life domains of chronic pelvic pain syndrome and shows superior effects to standard drug treatment.

View Source 2024
Meta-Analysis Men's Health / Urology

Effect of Combined Herbal Medicine and Electroacupuncture Treatment for Chronic Pelvic Pain Syndrome (CPPS): A Meta-Analysis

윤정호, 김상민, 이동현, et al. Prostate (2024)
12.3 points NIH-CPSI Reduction
789 subjects Total Subjects
11 RCTs Included RCTs

Summary

A meta-analysis analyzing the effect of combined herbal medicine and electroacupuncture treatment in male patients with CPPS (NIH Category IIIA/IIIB). Eleven randomized controlled trials (total 789 subjects) were included, and the combined herbal medicine-electroacupuncture group showed an average NIH-CPSI total score reduction of 12.3 points, significantly superior to the drug alone group.

Key Conclusion

Combined herbal medicine and electroacupuncture treatment is effective across all pain, urinary, and quality of life domains of chronic pelvic pain syndrome and shows superior effects to standard drug treatment.

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Meta-Analysis ENT Disorders

Antibiotic Replacement Potential of Eungyo-san for Pediatric Acute Otitis Media: A Meta-analysis

Woo JH, Kang HW, Cha YY, et al.

International Journal of Pediatric Otorhinolaryngology (2024)

84% Symptom Resolution Rate
11 studies Analyzed Studies
924 subjects Total Participants

Herbal medicine demonstrates equivalent efficacy to antibiotics in mild-to-moderate pediatric acute otitis media and may serve as an alternative to antibiotic overuse.

View Source 2024
Meta-Analysis ENT Disorders

Antibiotic Replacement Potential of Eungyo-san for Pediatric Acute Otitis Media: A Meta-analysis

Woo JH, Kang HW, Cha YY, et al. International Journal of Pediatric Otorhinolaryngology (2024)
84% Symptom Resolution Rate
11 studies Analyzed Studies
924 subjects Total Participants

Summary

Eleven RCTs (924 subjects total) on herbal medicine treatment for pediatric acute otitis media were meta-analyzed. The herbal medicine (Eungyo-san, Hyungaeyongyo-tang, etc.) monotherapy group demonstrated an 84% symptom resolution rate, non-inferior to the antibiotic group (88%). Side effects such as gut microbiota disruption were significantly fewer in the herbal group.

Key Conclusion

Herbal medicine demonstrates equivalent efficacy to antibiotics in mild-to-moderate pediatric acute otitis media and may serve as an alternative to antibiotic overuse.

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Before-After Neurological Disorders

Effect of Banhabaekchulcheonma-tang for Residual Dizziness in BPPV: A Pre-Post Comparison Study

Gu BM, Seol IC, Kim YS, et al.

Journal of Vestibular Research (2023)

52% DHI Reduction Rate
74% Dizziness Resolution
54 subjects Participants

Banhabaekchulcheonma-tang is effective for rapid resolution of residual dizziness after BPPV canalith repositioning.

View Source 2023
Before-After Neurological Disorders

Effect of Banhabaekchulcheonma-tang for Residual Dizziness in BPPV: A Pre-Post Comparison Study

Gu BM, Seol IC, Kim YS, et al. Journal of Vestibular Research (2023)
52% DHI Reduction Rate
74% Dizziness Resolution
54 subjects Participants

Summary

Fifty-four BPPV patients with residual dizziness persisting more than 2 weeks after canalith repositioning received Banhabaekchulcheonma-tang for 4 weeks. DHI scores decreased by an average of 52%, with complete residual dizziness resolution rate reaching 74%. Gait stability (TUG) also improved significantly.

Key Conclusion

Banhabaekchulcheonma-tang is effective for rapid resolution of residual dizziness after BPPV canalith repositioning.

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RCT Neurological Disorders

Effect of Combined Jinmu-tang and Vestibular Rehabilitation for Geriatric Vertigo: A Randomized Controlled Trial

Sung WS, Hong JW, Park SH, et al.

Geriatrics & Gerontology International (2024)

56% DHI Reduction Rate
108 subjects Participants
8 weeks Treatment Period

Adjunctive Jinmu-tang enhances vestibular rehabilitation effects in geriatric vertigo and reduces fall risk.

View Source 2024
RCT Neurological Disorders

Effect of Combined Jinmu-tang and Vestibular Rehabilitation for Geriatric Vertigo: A Randomized Controlled Trial

Sung WS, Hong JW, Park SH, et al. Geriatrics & Gerontology International (2024)
56% DHI Reduction Rate
108 subjects Participants
8 weeks Treatment Period

Summary

One hundred eight patients aged 65 or older with chronic vertigo were assigned to vestibular rehabilitation monotherapy or rehabilitation plus Jinmu-tang combination groups for 8 weeks of treatment. The combination group demonstrated a 56% reduction in DHI, significantly superior to monotherapy (38%), with greater improvement also in fall fear (FES-I).

Key Conclusion

Adjunctive Jinmu-tang enhances vestibular rehabilitation effects in geriatric vertigo and reduces fall risk.

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Meta-Analysis Mental Health

Effect of Meditation Combined with Herbal Medicine on Chronic Anxiety: A Meta-Analysis

Kim CH, Baek YH, Jeon SW, et al.

Journal of Psychosomatic Research (2023)

14 RCTs Analyzed RCTs
-4.21 BAI MD
Synergistic effect Combination benefit

The combination of meditation and herbal medicine provides synergistic effects for chronic anxiety.

View Source 2023
Meta-Analysis Mental Health

Effect of Meditation Combined with Herbal Medicine on Chronic Anxiety: A Meta-Analysis

Kim CH, Baek YH, Jeon SW, et al. Journal of Psychosomatic Research (2023)
14 RCTs Analyzed RCTs
-4.21 BAI MD
Synergistic effect Combination benefit

Summary

Fourteen RCTs evaluating the combined effects of meditation and herbal medicine on chronic anxiety were meta-analyzed. The combination group showed additional BAI score reduction (MD: -4.21) compared to monotherapy.

Key Conclusion

The combination of meditation and herbal medicine provides synergistic effects for chronic anxiety.

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RCT Mental Health

Randomized Controlled Trial of Moxibustion Combined with Herbal Medicine for Sleep Disorders in the Elderly

Seo DW, Park BS, Lee SY, et al.

Geriatrics & Gerontology International (2024)

6.2 points PSQI reduction
80 patients Participants
Moxibustion + herbs Optimal combination

Combination of moxibustion and herbal medicine is more effective than monotherapy for sleep disorders in the elderly.

View Source 2024
RCT Mental Health

Randomized Controlled Trial of Moxibustion Combined with Herbal Medicine for Sleep Disorders in the Elderly

Seo DW, Park BS, Lee SY, et al. Geriatrics & Gerontology International (2024)
6.2 points PSQI reduction
80 patients Participants
Moxibustion + herbs Optimal combination

Summary

Eighty elderly patients aged 65 or older with sleep disorders were compared between a moxibustion plus herbal medicine group and herbal medicine alone group for 8 weeks. The combination group showed a 6.2-point reduction in PSQI, significantly superior to the monotherapy group (3.8 points).

Key Conclusion

Combination of moxibustion and herbal medicine is more effective than monotherapy for sleep disorders in the elderly.

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Cross-Sectional Digestive Disorders

Effect of Herbal Medicine (Banhahubak-tang) on Functional Dyspepsia with Anxiety: A Cross-Sectional Analysis

Woo HS, Cho HJ, Nam DH, et al.

Functional Dyspepsia Research (2023)

160 patients Participants
38% Dyspepsia reduction
32% Anxiety reduction

Banhahubak-tang is effective for the simultaneous management of anxiety and functional dyspepsia.

View Source 2023
Cross-Sectional Digestive Disorders

Effect of Herbal Medicine (Banhahubak-tang) on Functional Dyspepsia with Anxiety: A Cross-Sectional Analysis

Woo HS, Cho HJ, Nam DH, et al. Functional Dyspepsia Research (2023)
160 patients Participants
38% Dyspepsia reduction
32% Anxiety reduction

Summary

Symptom differences were analyzed in 160 patients with functional dyspepsia comorbid with anxiety according to Banhahubak-tang use. Both FD symptoms (-38%) and anxiety (-32%) were significantly lower in the user group.

Key Conclusion

Banhahubak-tang is effective for the simultaneous management of anxiety and functional dyspepsia.

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Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Pediatric Acupuncture and Herbal Medicine for Children with Separation Anxiety Disorder

Suh JW, Shin MK, Kang JH, et al.

Child Psychiatry & Human Development (2023)

46% Separation anxiety reduction
30 patients Participants
8 weeks Treatment duration

Combination of pediatric acupuncture and herbal medicine is effective in alleviating symptoms in children with separation anxiety disorder.

View Source 2023
Before-After Pediatric / Adolescent Care

Pre-Post Comparison Study of Pediatric Acupuncture and Herbal Medicine for Children with Separation Anxiety Disorder

Suh JW, Shin MK, Kang JH, et al. Child Psychiatry & Human Development (2023)
46% Separation anxiety reduction
30 patients Participants
8 weeks Treatment duration

Summary

Pediatric acupuncture plus herbal medicine (Gammaekdaejo-tang) was applied to 30 children with separation anxiety disorder for 8 weeks. SASC separation anxiety scores decreased by 46% and parent-reported behavioral problems improved.

Key Conclusion

Combination of pediatric acupuncture and herbal medicine is effective in alleviating symptoms in children with separation anxiety disorder.

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